Erythromycin( NSC 55929 )

Catalog No. M10494 CAS No. 114-07-8

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Product Name

Erythromycin
Note

Research use only, not for human use.
Brief Description

Erythromycin, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis.
Description

Erythromycin, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis.
In Vitro

——
In Vivo

——
Synonyms

NSC 55929
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

23S rRNA| 50S ribosome
Research Area

Infection
Indication

——

CAS Number

114-07-8
Formula Weight

733.93
Molecular Formula

C37H67NO13
Purity

>98% (HPLC)
Solubility

Ethanol: 147 mg/mL (200.29 mM); Water: 3 mg/mL (4.08 mM); DMSO: 147 mg/mL (200.29 mM)
SMILES

C[C@@H]([C@@H]([C@H](C(O[C@@H]([C@@]([C@H](O)[C@@H](C)C1=O)(C)O)CC)=O)C)O[C@H]2C[C@]([C@@H](O)[C@H](C)O2)(OC)C)[C@H]([C@](C)(O)C[C@H]1C)O[C@H](O[C@@H](C[C@@H]3N(C)C)C)[C@@H]3O
Chemical Name

(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione

1.Moazed D, Noller HF. Biochimie. 1987 Aug;69(8):879-84.

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