JPD447

CAS No. 2883235-86-5

JPD447( —— )

Catalog No. M36587 CAS No. 2883235-86-5

JPD447 is a MAC-0547630 derivative that potentiates UppS inhibitors of β-lactam antibiotics with antimicrobial activity and can be used to study bacterial infections.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 144 Get Quote
5MG 223 Get Quote
10MG 359 Get Quote
25MG 701 Get Quote
50MG 1187 Get Quote
100MG 1782 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    JPD447
  • Note
    Research use only, not for human use.
  • Brief Description
    JPD447 is a MAC-0547630 derivative that potentiates UppS inhibitors of β-lactam antibiotics with antimicrobial activity and can be used to study bacterial infections.
  • Description
    JPD447, a MAC-0547630 derivative, is a novel class of UppS inhibitor to potentiate β-lactam antibiotics.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2883235-86-5
  • Formula Weight
    338.42
  • Molecular Formula
    C20H23FN4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (295.49 mM; Ultrasonic (<80°C)
  • SMILES
    FC1=CC=C(C=C1)C=2C=NN3C2N=C(C=C3N4CCCCCC4)CC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Workman SD, et al. Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria. J Med Chem. 2021 Sep 23;64(18):13540-13550. ?
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