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Erastin2

CAS No. 1695533-44-8

Erastin2( —— )

Catalog No. M34807 CAS No. 1695533-44-8

Erastin2 is a ferroptosis inducer and inhibitor of the system xc- cystine/glutamate transporter.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Erastin2
  • Note
    Research use only, not for human use.
  • Brief Description
    Erastin2 is a ferroptosis inducer and inhibitor of the system xc- cystine/glutamate transporter.
  • Description
    Erastin2 is a ferroptosis inducer and a potent, selective inhibitor of the system xc(-) cystine/glutamate transporter.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Ferroptosis
  • Recptor
    Ferroptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1695533-44-8
  • Formula Weight
    623.14
  • Molecular Formula
    C36H35ClN4O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (160.48 mM; Ultrasonic )
  • SMILES
    CC(C)Oc1ccc(cc1-n1c(CN2CCN(CC2)C(=O)COc2ccc(Cl)cc2)nc2ccccc2c1=O)-c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Cao JY, et al. A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity. Cell Rep. 2019 Feb 5;26(6):1544-1556.e8. ?
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