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Endoxifen

CAS No. 112093-28-4

Endoxifen ( —— )

Catalog No. M10432 CAS No. 112093-28-4

A metabolite of tamoxifen, orally active non-steroidal selective estrogen receptor modulator (SERM) for the treatment of estrogen receptor-positive breast cancer.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 120 In Stock
10MG 192 In Stock
25MG 356 In Stock
50MG 555 In Stock
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Biological Information

  • Product Name
    Endoxifen
  • Note
    Research use only, not for human use.
  • Brief Description
    A metabolite of tamoxifen, orally active non-steroidal selective estrogen receptor modulator (SERM) for the treatment of estrogen receptor-positive breast cancer.
  • Description
    A metabolite of tamoxifen, orally active non-steroidal selective estrogen receptor modulator (SERM) for the treatment of estrogen receptor-positive breast cancer.Breast Cancer Phase 1 Clinical
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    Estrogen Receptor/ERR
  • Recptor
    ER;ERR;hERGPotassiumChannel
  • Research Area
    Cancer
  • Indication
    Breast Cancer

Chemical Information

  • CAS Number
    112093-28-4
  • Formula Weight
    373.49
  • Molecular Formula
    C25H27NO2
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCNC)C3=CC=CC=C3
  • Chemical Name
    Phenol, 4-[(1Z)-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Brauch H, et al. Clin Chem. 2009 Oct;55(10):1770-82.
2. Markopoulos C, et al. World J Clin Oncol. 2014 Aug 10;5(3):374-81.
3. Mugundu GM, et al. Drug Metab Dispos. 2012 Feb;40(2):389-96.
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