Cart
sales@molnova.com
Elobixibat
CAS No. 439087-18-0
Elobixibat( A-3309 | AZD-7806 | AJG-533 )
Catalog No. M14492 CAS No. 439087-18-0
An orally available, potent and selective ileal bile acid transporter (IBAT) inhibitor for the treatment of constipation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 579 | In Stock |
|
| 10MG | 824 | In Stock |
|
| 25MG | 1233 | In Stock |
|
| 50MG | 1665 | In Stock |
|
| 100MG | 2232 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameElobixibat
-
NoteResearch use only, not for human use.
-
Brief DescriptionAn orally available, potent and selective ileal bile acid transporter (IBAT) inhibitor for the treatment of constipation.
-
DescriptionAn orally available, potent and selective ileal bile acid transporter (IBAT) inhibitor for the treatment of constipation.Other Indication Phase 2 Clinical.
-
In Vitro——
-
In Vivo——
-
SynonymsA-3309 | AZD-7806 | AJG-533
-
PathwayMembrane Transporter/Ion Channel
-
TargetASBT Transporter
-
RecptorASBT Transporter
-
Research AreaOther Indications
-
IndicationOther Disease
Chemical Information
-
CAS Number439087-18-0
-
Formula Weight695.89
-
Molecular FormulaC36H45N3O7S2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 250 mg/mL (359.25 mM)
-
SMILESO=C(O)CNC([C@@H](C1=CC=CC=C1)NC(COC2=C(SC)C=C(C3=C2)N(C4=CC=CC=C4)CC(CCCC)(CCCC)CS3(=O)=O)=O)=O
-
Chemical NameGlycine, (2R)-N-[[[3,3-dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-1,1-dioxido-5-phenyl-1,5-benzothiazepin-8-yl]oxy]acetyl]-2-phenylglycyl- (9CI)
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Chey WD, et al. Gastroenterol. 2014 May;109(5):782.
2. Wong BS, et al. Expert Opin Investig Drugs. 2013 Feb;22(2):277-84.
3. Wong BS, et al. Am J Gastroenterol. 2011 Dec;106(12):2154-64.
molnova catalog
related products
-
Lopixibat chloride
Lopixibat chloride (LUM-001, HP-625) is a potent, selectiove, oral inhibitor of sodium bile acid cotransporter and Ileal bile acid transporter (IBAT).
-
Elobixibat
An orally available, potent and selective ileal bile acid transporter (IBAT) inhibitor for the treatment of constipation.
-
Volixibat
A highly potent and selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT) in development for the treatment of nonalcoholic steatohepatitis (NASH).
