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Elamipretide

CAS No. 736992-21-5

Elamipretide( SS-31 | MTP-131 | Bendavia )

Catalog No. M15818 CAS No. 736992-21-5

Elamipretide (SS-31, MTP-131, Bendavia) is a novel cell-permeable antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that targets inner mitochondrial membrane and prevents oxidative damage of neuronal cells and other cell types.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 66 In Stock
5MG 120 In Stock
10MG 187 In Stock
25MG 338 In Stock
50MG 506 In Stock
100MG 647 In Stock
200MG 896 In Stock
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Biological Information

  • Product Name
    Elamipretide
  • Note
    Research use only, not for human use.
  • Brief Description
    Elamipretide (SS-31, MTP-131, Bendavia) is a novel cell-permeable antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that targets inner mitochondrial membrane and prevents oxidative damage of neuronal cells and other cell types.
  • Description
    Elamipretide (SS-31, MTP-131, Bendavia) is a novel cell-permeable antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that targets inner mitochondrial membrane and prevents oxidative damage of neuronal cells and other cell types; prevents mitochondrial depolarization, reduces islet cell apoptosis, increases islet cell yield, and improves posttransplantation function.Other Indication Phase 3 Clinical.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SS-31 | MTP-131 | Bendavia
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Other Targets
  • Research Area
    Other Indications
  • Indication
    Other Disease

Chemical Information

  • CAS Number
    736992-21-5
  • Formula Weight
    639.802
  • Molecular Formula
    C32H49N9O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 29 mg/mL (45.33 mM)
  • SMILES
    O=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](CCCCN)NC([C@H](CC2=C(C)C=C(O)C=C2C)NC([C@@H](CCCNC(N)=N)N)=O)=O)=O
  • Chemical Name
    (S)-6-amino-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-((R)-2-amino-5-guanidinopentanamido)-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)hexanamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Thomas DA, et al. J Am Soc Nephrol. 2007 Jan;18(1):213-22. 2. Zhao K, et al. Biochem Pharmacol. 2005 Dec 5;70(12):1796-806. 3. Mizuguchi Y, et al. Am J Physiol Renal Physiol. 2008 Nov;295(5):F1545-53.
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