Pinocembrin( (+)-Pinocoembrin | Dihydrochrysin | Galangin flavanone )

Catalog No. M18610 CAS No. 480-39-7

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Pinocembrin
Note

Research use only, not for human use.
Brief Description

Pinocembrin is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.
Description

Pinocembrin is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.(In Vitro):Pinocembrin (5, 10, 25, 50, 100 or 200 μM, 24 hours) significantly reduces cell viability of RBL-2H3 cells.Pinocembrin (25 or 50 μM) suppresses iNOS, PGE-2 and COX-2 levels, increases p38-Mapk and IкB-α, and inhibits phosphorylation of IкB-α.
In Vitro

Pinocembrin (5, 10, 25, 50, 100 or 200 μM, 24 hours) significantly reduces cell viability of RBL-2H3 cells.Pinocembrin (25 or 50 μM) suppresses iNOS, PGE-2 and COX-2 levels, increases p38-Mapk and IкB-α, and inhibits phosphorylation of IкB-α. Cell Viability Assay Cell Line:RBL-2H3 cells Concentration:5, 10, 25, 50, 100 or 200 μM Incubation Time:24 hours Result:Decreased cell viability by ～50% at ≥ 100 μM. Showed 75% cell viability at lower concentrations.
In Vivo

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Synonyms

(+)-Pinocoembrin | Dihydrochrysin | Galangin flavanone
Pathway

Others
Target

Other Targets
Recptor

NF-κB
Research Area

Inflammation/Immunology|Neurological Disease
Indication

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1. Saad MA, et al. Pharmacol Rep. 2015 Feb;67(1):115-22.

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