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Efonidipine
CAS No. 111011-63-3
Efonidipine( NZ-105 | (±)-Efonidipine )
Catalog No. M10409 CAS No. 111011-63-3
Efonidipine (NZ-105) is a potent, dual T-type and L-type calcium channel blocker.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 28 | Get Quote |
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| 5MG | 43 | Get Quote |
|
| 10MG | 65 | Get Quote |
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| 25MG | 114 | Get Quote |
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| 50MG | 162 | Get Quote |
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| 100MG | 318 | Get Quote |
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| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameEfonidipine
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NoteResearch use only, not for human use.
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Brief DescriptionEfonidipine (NZ-105) is a potent, dual T-type and L-type calcium channel blocker.
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DescriptionEfonidipine (NZ-105) is a potent, dual T-type and L-type calcium channel blocker, exhibits antihypertensive effect through vasodilatation; increases coronary blood flow by blocking L & T-type calcium channels and attenuates myocardial ischaemia, lowers blood pressure in cerebral resistance vessels and prevents hypertension induced brain damage; increases glomerular filtration rate without increasing intra-glomerular pressure and filtration fraction.
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In Vitro——
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In Vivo——
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SynonymsNZ-105 | (±)-Efonidipine
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PathwayGPCR/G Protein
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TargetCalcium Channel
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RecptorCalciumChannel
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Research AreaCardiovascular Disease
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Indication——
Chemical Information
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CAS Number111011-63-3
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Formula Weight631.6552
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Molecular FormulaC34H38N3O7P
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C(C1=C(C)NC(C)=C(P2(OCC(C)(C)CO2)=O)C1C3=CC=CC([N+]([O-])=O)=C3)OCCN(CC4=CC=CC=C4)C5=CC=CC=C5
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Chemical Name3-Pyridinecarboxylic acid, 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[phenyl(phenylmethyl)amino]ethyl ester
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Masuda Y, et al. Arch Int Pharmacodyn Ther. 1990 Mar-Apr;304:247-64.
2. Tamura T, et al. Naunyn Schmiedebergs Arch Pharmacol. 1991 Apr;343(4):405-10.
3. Shudo C, et al. Gen Pharmacol. 1994 Nov;25(7):1451-8.
4. Yamashita T, et al. Jpn J Pharmacol. 1991 Nov;57(3):337-48.
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