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EZH2-IN-3
CAS No. 1377997-28-8
EZH2-IN-3 ( EZH2-IN-3;EZH2 inhibitor 3; EZH2-inhibitor-3 )
Catalog No. M11560 CAS No. 1377997-28-8
EZH2-IN-3 is a highly selective small molecule inhibitor of EZH2 and EZH1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameEZH2-IN-3
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NoteResearch use only, not for human use.
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Brief DescriptionEZH2-IN-3 is a highly selective small molecule inhibitor of EZH2 and EZH1.
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DescriptionEZH2-IN-3 is a highly selective small molecule inhibitor of EZH2 and EZH1 with IC50 of 21/197/213 nM for wt EZH2/EZH2 Y641N/wt EZH1 respectively; suppresses global histone H3-lysine 27 methylation and cause selective proliferation defects.
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SynonymsEZH2-IN-3;EZH2 inhibitor 3; EZH2-inhibitor-3
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PathwayChromatin/Epigenetic
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TargetHMTase
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RecptorHMTase
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Research Area——
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Indication——
Chemical Information
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CAS Number1377997-28-8
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Formula Weight490.00
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Molecular FormulaC27H28ClN5O2
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(NC1CC(C)(C)NC(C)(C)C1)C2=CC=C(OC3=CC=CC(C4=CC=NN=C4)=C3C#N)C(Cl)=C2
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Chemical Name3-chloro-4-(2-cyano-3-(pyridazin-4-yl)phenoxy)-N-(2,2,6,6-tetramethylpiperidin-4-yl)benzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Garapaty-Rao S, et al. Chem Biol. 2013 Nov 21;20(11):1329-39.
molnova catalog
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