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EZH2-IN-15
CAS No. 2098545-98-1
EZH2-IN-15( —— )
Catalog No. M36050 CAS No. 2098545-98-1
EZH2-IN-15 (SHR2554) is a specific inhibitor of the zeste 2 histone modification enhancer (EZH2).EZH2 is aberrantly overexpressed in many human cancers and controls adaptive responses by regulating Treg activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 242 | Get Quote |
|
| 5MG | 345 | Get Quote |
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| 10MG | 527 | Get Quote |
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| 25MG | 809 | Get Quote |
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| 50MG | 1086 | Get Quote |
|
| 100MG | 1431 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameEZH2-IN-15
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NoteResearch use only, not for human use.
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Brief DescriptionEZH2-IN-15 (SHR2554) is a specific inhibitor of the zeste 2 histone modification enhancer (EZH2).EZH2 is aberrantly overexpressed in many human cancers and controls adaptive responses by regulating Treg activity.
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DescriptionEZH2-IN-15 (SHR2554) is a EZH2 inhibitor. EZH2-IN-15 has anti-tumor activity, and can be used for research of H3K27me3-dependent tumors.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorHistone Methyltransferase
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Research Area——
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Indication——
Chemical Information
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CAS Number2098545-98-1
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Formula Weight548.72
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Molecular FormulaC32H44N4O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (227.80 mM; Ultrasonic )
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SMILESCCN(C1CCOCC1)c1cc2oc(CN3CCCCC3)cc2c(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1CC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Dale B, et al. Targeting Triple-Negative Breast Cancer by a Novel Proteolysis Targeting Chimera Degrader of Enhancer of Zeste Homolog 2. ACS Pharmacol Transl Sci. 2022 Jun 24;5(7):491-507.?
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