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Home - Products - Membrane Transporter/Ion Channel - AMPK - ETC-1002

ETC-1002

CAS No. 738606-46-7

ETC-1002 ( ESP-55016;Bempedoic acid )

Catalog No. M15823 CAS No. 738606-46-7

A small molecule regulator of lipid and carbohydrate metabolism that targets ACC (acetyl-CoA carboxylase) with IC50 of 29 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 27 In Stock
5MG 43 In Stock
10MG 60 In Stock
25MG 114 In Stock
50MG 206 In Stock
100MG 332 In Stock
500MG 797 In Stock
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Biological Information

  • Product Name
    ETC-1002
  • Note
    Research use only, not for human use.
  • Brief Description
    A small molecule regulator of lipid and carbohydrate metabolism that targets ACC (acetyl-CoA carboxylase) with IC50 of 29 uM.
  • Description
    A small molecule regulator of lipid and carbohydrate metabolism that targets ACC (acetyl-CoA carboxylase) with IC50 of 29 uM without activating the AMPK pathway in vitro; reduces circulating proatherogenic lipoproteins, hepatic lipids, and body weight in a hamster model of hyperlipidemia.Diabetes Phase 2 Clinical
  • Synonyms
    ESP-55016;Bempedoic acid
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    AMPK
  • Recptor
    ACL
  • Research Area
    Metabolic Disease
  • Indication
    Diabetes

Chemical Information

  • CAS Number
    738606-46-7
  • Formula Weight
    344.49
  • Molecular Formula
    C19H36O5
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C(O)C(C)(C)CCCCCC(O)CCCCCC(C)(C)C(O)=O
  • Chemical Name
    Pentadecanedioic acid, 8-hydroxy-2,2,14,14-tetramethyl-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Pinkosky SL, et al. J Lipid Res. 2013 Jan;54(1):134-51.
2. Cramer CT, et al. J Lipid Res. 2004 Jul;45(7):1289-301.
3. Filippov S, et al. J Lipid Res. 2013 Aug;54(8):2095-108.
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