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ETC-1002
CAS No. 738606-46-7
ETC-1002 ( ESP-55016;Bempedoic acid )
Catalog No. M15823 CAS No. 738606-46-7
A small molecule regulator of lipid and carbohydrate metabolism that targets ACC (acetyl-CoA carboxylase) with IC50 of 29 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 27 | In Stock |
|
| 5MG | 43 | In Stock |
|
| 10MG | 60 | In Stock |
|
| 25MG | 114 | In Stock |
|
| 50MG | 206 | In Stock |
|
| 100MG | 332 | In Stock |
|
| 500MG | 797 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameETC-1002
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NoteResearch use only, not for human use.
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Brief DescriptionA small molecule regulator of lipid and carbohydrate metabolism that targets ACC (acetyl-CoA carboxylase) with IC50 of 29 uM.
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DescriptionA small molecule regulator of lipid and carbohydrate metabolism that targets ACC (acetyl-CoA carboxylase) with IC50 of 29 uM without activating the AMPK pathway in vitro; reduces circulating proatherogenic lipoproteins, hepatic lipids, and body weight in a hamster model of hyperlipidemia.Diabetes Phase 2 Clinical
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SynonymsESP-55016;Bempedoic acid
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PathwayMembrane Transporter/Ion Channel
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TargetAMPK
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RecptorACL
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Research AreaMetabolic Disease
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IndicationDiabetes
Chemical Information
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CAS Number738606-46-7
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Formula Weight344.49
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Molecular FormulaC19H36O5
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C(O)C(C)(C)CCCCCC(O)CCCCCC(C)(C)C(O)=O
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Chemical NamePentadecanedioic acid, 8-hydroxy-2,2,14,14-tetramethyl-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Pinkosky SL, et al. J Lipid Res. 2013 Jan;54(1):134-51.
2. Cramer CT, et al. J Lipid Res. 2004 Jul;45(7):1289-301.
3. Filippov S, et al. J Lipid Res. 2013 Aug;54(8):2095-108.
2. Cramer CT, et al. J Lipid Res. 2004 Jul;45(7):1289-301.
3. Filippov S, et al. J Lipid Res. 2013 Aug;54(8):2095-108.
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