Dopamine

CAS No. 51-61-6

Dopamine( —— )

Catalog No. M24487 CAS No. 51-61-6

Dopamine is an inotropic vasopressor agent and dopamine receptor agonist used in neurological diseases.?

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Dopamine
  • Note
    Research use only, not for human use.
  • Brief Description
    Dopamine is an inotropic vasopressor agent and dopamine receptor agonist used in neurological diseases.?
  • Description
    Dopamine is an inotropic vasopressor agent and dopamine receptor agonist used in neurological diseases.?
  • In Vitro
    Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) strongly stimulates human umbilical vein endothelial cells (HUVECs) proliferation. The stimulatory effect of VPF/VEGF is abrogated by Dopamine (1 μM; 24hours). Cell Proliferation Assay Cell Line:HUVECs Concentration:1 μMIncubation Time:24 hours Result:Inhibited VPF/VEGF-induced HUVEC proliferation specifically through its D2 receptor.
  • In Vivo
    Dopamine (50 mg/kg; i.p. injection; days 1-7) strongly and selectively inhibits the vascular permeabilizing and angiogenic activities of VPF/VEGF. Animal Model:Syngeneic C3Heb/FeJ mice with MOT ascites tumors Dosage:50 mg/kg Administration:I.p. injection; 7 days Result:Corresponding to ~5% of the median lethal dose (LD50) in mice) beginning at 24 hours after tumor-cell injection and continuing daily for 7 days.
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Dopamine Receptor
  • Recptor
    dopamine
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    51-61-6
  • Formula Weight
    153.18
  • Molecular Formula
    C8H11NO2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    C1=CC(=C(C=C1CCN)O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Berke, Joshua D . What does dopamine mean?[J]. Nature Neuroscience, 2018.
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