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Dopamine
CAS No. 51-61-6
Dopamine( —— )
Catalog No. M24487 CAS No. 51-61-6
Dopamine is an inotropic vasopressor agent and dopamine receptor agonist used in neurological diseases.?
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 49 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameDopamine
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NoteResearch use only, not for human use.
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Brief DescriptionDopamine is an inotropic vasopressor agent and dopamine receptor agonist used in neurological diseases.?
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DescriptionDopamine is an inotropic vasopressor agent and dopamine receptor agonist used in neurological diseases.?
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In VitroVascular permeability factor/vascular endothelial growth factor (VPF/VEGF) strongly stimulates human umbilical vein endothelial cells (HUVECs) proliferation. The stimulatory effect of VPF/VEGF is abrogated by Dopamine (1 μM; 24hours). Cell Proliferation Assay Cell Line:HUVECs Concentration:1 μMIncubation Time:24 hours Result:Inhibited VPF/VEGF-induced HUVEC proliferation specifically through its D2 receptor.
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In VivoDopamine (50 mg/kg; i.p. injection; days 1-7) strongly and selectively inhibits the vascular permeabilizing and angiogenic activities of VPF/VEGF. Animal Model:Syngeneic C3Heb/FeJ mice with MOT ascites tumors Dosage:50 mg/kg Administration:I.p. injection; 7 days Result:Corresponding to ~5% of the median lethal dose (LD50) in mice) beginning at 24 hours after tumor-cell injection and continuing daily for 7 days.
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Synonyms——
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PathwayGPCR/G Protein
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TargetDopamine Receptor
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Recptordopamine
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Research Area——
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Indication——
Chemical Information
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CAS Number51-61-6
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Formula Weight153.18
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Molecular FormulaC8H11NO2
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESC1=CC(=C(C=C1CCN)O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Berke, Joshua D . What does dopamine mean?[J]. Nature Neuroscience, 2018.
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