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Dilmapimod
CAS No. 444606-18-2
Dilmapimod( SB-681323 | GW 681323 )
Catalog No. M24403 CAS No. 444606-18-2
Dilmapimod is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 35 | In Stock |
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| 10MG | 58 | In Stock |
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| 25MG | 110 | In Stock |
|
| 50MG | 178 | In Stock |
|
| 100MG | 332 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDilmapimod
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NoteResearch use only, not for human use.
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Brief DescriptionDilmapimod is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.
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DescriptionDilmapimod is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.
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In VitroDilmapimod (SB-681323) potently inhibits p38 MAPK signaling, measured by inhibition of sorbitol-induced pHSP27 expression.
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In Vivo——
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SynonymsSB-681323 | GW 681323
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PathwayAutophagy
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TargetAutophagy
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RecptorAutophagy|p38 MAPK
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Research Area——
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Indication——
Chemical Information
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CAS Number444606-18-2
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Formula Weight456.42
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Molecular FormulaC23H19F3N4O3
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Purity>98% (HPLC)
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SolubilityDMSO:125 mg/mL (273.87 mM; Need ultrasonic)
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SMILESCc(cc(cc1)F)c1-c1c(C=CC(N2c(c(F)ccc3)c3F)=O)c2nc(NC(CO)CO)n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Singh D, et al. A randomized, placebo-controlled study of the effects of the p38 MAPK inhibitor SB-681323 on blood biomarkers of inflammation in COPD patients. J Clin Pharmacol. 2010 Jan;50(1):94-100.
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