Dilmapimod

CAS No. 444606-18-2

Dilmapimod ( SB-681323; GW 681323 )

Catalog No. M24403 CAS No. 444606-18-2

Dilmapimod is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 35 In Stock
10MG 58 In Stock
25MG 110 In Stock
50MG 178 In Stock
100MG 332 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    Dilmapimod
  • Note
    Research use only, not for human use.
  • Brief Description
    Dilmapimod is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.
  • Description
    Dilmapimod is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.
  • Synonyms
    SB-681323; GW 681323
  • Pathway
    Autophagy
  • Target
    Autophagy
  • Recptor
    Autophagy;p38 MAPK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    444606-18-2
  • Formula Weight
    456.4
  • Molecular Formula
    C23H19F3N4O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL (273.87 mM; Need ultrasonic)
  • SMILES
    Cc(cc(cc1)F)c1-c1c(C=CC(N2c(c(F)ccc3)c3F)=O)c2nc(NC(CO)CO)n1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Singh D, et al. A randomized, placebo-controlled study of the effects of the p38 MAPK inhibitor SB-681323 on blood biomarkers of inflammation in COPD patients. J Clin Pharmacol. 2010 Jan;50(1):94-100.
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