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Cilostazol

CAS No. 73963-72-1

Cilostazol ( OPC 13013;OPC 21 )

Catalog No. M15825 CAS No. 73963-72-1

Cilostazol (OPC 13013, OPC 21) is a potent inhibitor of PDE3A with IC50 of 0.2 uM; inhibits platelet aggregation and has considerable antithrombotic effects in vivo.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Cilostazol
  • Note
    Research use only, not for human use.
  • Brief Description
    Cilostazol (OPC 13013, OPC 21) is a potent inhibitor of PDE3A with IC50 of 0.2 uM; inhibits platelet aggregation and has considerable antithrombotic effects in vivo.
  • Description
    Cilostazol (OPC 13013, OPC 21) is a potent inhibitor of PDE3A with IC50 of 0.2 uM; inhibits platelet aggregation and has considerable antithrombotic effects in vivo. The compound relaxes vascular smooth muscle and inhibits mitogenesis and migration of vascular smooth muscle cells; also upregulates autophagy via SIRT1 activation, has preventive effects on various central nervous system (CNS) diseases.Stroke Approved
  • Synonyms
    OPC 13013;OPC 21
  • Pathway
    Angiogenesis
  • Target
    PDE
  • Recptor
    PDE3
  • Research Area
    Neurological Disease
  • Indication
    Stroke

Chemical Information

  • CAS Number
    73963-72-1
  • Formula Weight
    369.46
  • Molecular Formula
    C20H27N5O2
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    C1CCC(CC1)N2C(=NN=N2)CCCCOC3=CC4=C(C=C3)NC(=O)CC4
  • Chemical Name
    2(1H)-Quinolinone, 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Schrr K, et al. Diabetes Obes Metab. 2002 Mar;4 Suppl 2:S14-9.
2. Lee HR, et al. PLoS One. 2015 Aug 5;10(8):e0134486.
3. Qi DS, et al. Brain Res. 2016 Dec 15;1653:67-74.
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