Dexpramipexole( R)-Pramipexole | KNS-760704 )

Catalog No. M10230 CAS No. 104632-28-2

A partial/full agonist of dopamine receptor with Ki of 3.9/2.2/0.5/5.1 nM for D2S/D2L/D3/D4, respeectively.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	873	Get Quote
100MG	Get Quote	Get Quote
200MG	Get Quote	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

Dexpramipexole
Note

Research use only, not for human use.
Brief Description

A partial/full agonist of dopamine receptor with Ki of 3.9/2.2/0.5/5.1 nM for D2S/D2L/D3/D4, respeectively.
Description

A partial/full agonist of dopamine receptor with Ki of 3.9/2.2/0.5/5.1 nM for D2S/D2L/D3/D4, respeectively; also possesses low/insignificant affinity (500–10,000 nM) for the 5-HT1A, 5-HT1B, 5-HT1D, and α2-adrenergic receptors; used for treating Parkinson's disease (PD) and restless legs syndrome (RLS).Alzheimer's Disease Phase 2 Clinical.
In Vitro

——
In Vivo

——
Synonyms

R)-Pramipexole | KNS-760704
Pathway

GPCR/G Protein
Target

Dopamine Receptor
Recptor

Dopamine Receptor
Research Area

Neurological Disease
Indication

Alzheimer Disease

Chemical Information

CAS Number

104632-28-2
Formula Weight

211.3271
Molecular Formula

C10H17N3S
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

CCCNC1CCC2=C(C1)SC(=N2)N
Chemical Name

2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, (6R)-

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Alavian KN, et al. Brain Res. 2012 Mar 29;1446:1-11. 2. Cudkowicz M, et al. Nat Med. 2011 Nov 20;17(12):1652-6. 3. Bozik ME, et al. J Clin Pharmacol. 2011 Aug;51(8):1177-85.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

Product			Quantity Required*
Name *			E-mail Address *
Organization *			Phone Number
Remarks