Desmethyl-VS-5584( Desmethyl-VS-5584 | Desmethyl-VS5584 )

Catalog No. M17217 CAS No. 1246535-95-4

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Desmethyl-VS-5584
Note

Research use only, not for human use.
Brief Description

Desmethyl-VS-5584 is a dimethyl analog of VS-5584, which is a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.
Description

Desmethyl-VS-5584 is a demethyl analogue of VS-5584, which is a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.
In Vitro

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In Vivo

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Synonyms

Desmethyl-VS-5584 | Desmethyl-VS5584
Pathway

Cell Cycle/DNA Damage
Target

PARP
Recptor

mTOR| PI3K
Research Area

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Indication

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CAS Number

1246535-95-4
Formula Weight

340.39
Molecular Formula

C16H20N8O
Purity

>98% (HPLC)
Solubility

——
SMILES

Nc1ncc(c2c3ncn(C(C)C)c3nc(N3CCOCC3)n2)cn1
Chemical Name

5-[9-(1-Methylethyl)-2-(4-morpholinyl)-9H-purin-6-yl]-2-pyrimidinamine

1. Shao Z,et al. VS-5584, a Novel PI3K-mTOR Dual Inhibitor, Inhibits Melanoma Cell Growth In Vitro and In Vivo. PLoS One. 2015 Jul 23;10(7).

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