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Demethyleneberberine

CAS No. 25459-91-0

Demethyleneberberine ( —— )

Catalog No. M18314 CAS No. 25459-91-0

Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either in vitro or in vivo.

Purity : 98%

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Biological Information

  • Product Name
    Demethyleneberberine
  • Note
    Research use only, not for human use.
  • Brief Description
    Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either in vitro or in vivo.
  • Description
    Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either in vitro or in vivo.Demethyleneberberine suppresses CYP2E1, hypoxia inducible factor α, and inducible nitric oxide synthase, which contributes to oxidative stress and restored sirtuin 1/AMP-activated protein kinase/peroxisome proliferator-activated receptor-γ coactivator-1α pathway-associated fatty acid oxidation in chronic ethanol-fed mice.
  • Synonyms
    ——
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Akt
  • Recptor
    CYP17;HIF;NOS
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    25459-91-0
  • Formula Weight
    324.35
  • Molecular Formula
    C19H18NO4+
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    Oc1cc2c3cc4ccc(OC)c(OC)c4c[n+]3CCc2cc1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhang P1,et al.J Pharmacol Exp Ther. 2015 Jan;352(1):139-47.
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