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Home - Products - GPCR/G Protein - Antibacterial - Delpazolid

Delpazolid

CAS No. 1219707-39-7

Delpazolid ( LCB01-0371;LCB 01-0371 )

Catalog No. M10827 CAS No. 1219707-39-7

A novel oxazolidinone antibiotic that shows good antibacterial activity (MSSA MIC50=1 ug/mL).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Delpazolid
  • Note
    Research use only, not for human use.
  • Brief Description
    A novel oxazolidinone antibiotic that shows good antibacterial activity (MSSA MIC50=1 ug/mL).
  • Description
    A novel oxazolidinone antibiotic that shows good antibacterial activity (MSSA MIC50=1 ug/mL); potently inhibits MSSA and MRSA clinical isolates with MIC of 0.5-2 and 0.5-4 ug/mL, respectively; shows more-potent protective effects (MSSA ED50=4.53 mg/kg) than Linezolid against systemic infections caused by Gram-positive and Gram-negative bacteria in mice model.Bacterial Infection Preclinical
  • Synonyms
    LCB01-0371;LCB 01-0371
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Others
  • Research Area
    Infection
  • Indication
    Bacterial Infection

Chemical Information

  • CAS Number
    1219707-39-7
  • Formula Weight
    308.31
  • Molecular Formula
    C14H17FN4O3
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C1O[C@@H](CO)CN1C2=CC=C(N3C=NN(C)CC3)C(F)=C2
  • Chemical Name
    (5R)-3-[3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Jeong JW, et al. Antimicrob Agents Chemother. 2010 Dec;54(12):5359-62.
2. Kim TS, et al. Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e02752-16.
3. Choi Y, et al. J Antimicrob Chemother. 2017 Oct 23. doi: 10.1093/jac/dkx367.
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