Delpazolid

Research use only, not for human use.

A novel oxazolidinone antibiotic that shows good antibacterial activity (MSSA MIC50=1 ug/mL).

A novel oxazolidinone antibiotic that shows good antibacterial activity (MSSA MIC50=1 ug/mL); potently inhibits MSSA and MRSA clinical isolates with MIC of 0.5-2 and 0.5-4 ug/mL, respectively; shows more-potent protective effects (MSSA ED50=4.53 mg/kg) than Linezolid against systemic infections caused by Gram-positive and Gram-negative bacteria in mice model.Bacterial Infection Preclinical

LCB01-0371;LCB 01-0371

GPCR/G Protein

Antibacterial

Others

Infection

Bacterial Infection

1219707-39-7

308.31

C14H17FN4O3

>98% (HPLC)

10 mM in DMSO

O=C1O[C@@H](CO)CN1C2=CC=C(N3C=NN(C)CC3)C(F)=C2

(5R)-3-[3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one

(-20℃)

With Ice Pack

≥ 2 years