Delpazolid

CAS No. 1219707-39-7

Delpazolid ( LCB01-0371;LCB 01-0371 )

Catalog No. M10827 CAS No. 1219707-39-7

A novel oxazolidinone antibiotic that shows good antibacterial activity (MSSA MIC50=1 ug/mL).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 72 In Stock
10MG 125 In Stock
25MG 260 In Stock
50MG 447 In Stock
100MG 624 In Stock
500MG 1305 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Delpazolid
  • Note
    Research use only, not for human use.
  • Brief Description
    A novel oxazolidinone antibiotic that shows good antibacterial activity (MSSA MIC50=1 ug/mL).
  • Description
    A novel oxazolidinone antibiotic that shows good antibacterial activity (MSSA MIC50=1 ug/mL); potently inhibits MSSA and MRSA clinical isolates with MIC of 0.5-2 and 0.5-4 ug/mL, respectively; shows more-potent protective effects (MSSA ED50=4.53 mg/kg) than Linezolid against systemic infections caused by Gram-positive and Gram-negative bacteria in mice model.Bacterial Infection Preclinical
  • Synonyms
    LCB01-0371;LCB 01-0371
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Others
  • Research Area
    Infection
  • Indication
    Bacterial Infection

Chemical Information

  • CAS Number
    1219707-39-7
  • Formula Weight
    308.31
  • Molecular Formula
    C14H17FN4O3
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C1O[C@@H](CO)CN1C2=CC=C(N3C=NN(C)CC3)C(F)=C2
  • Chemical Name
    (5R)-3-[3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Jeong JW, et al. Antimicrob Agents Chemother. 2010 Dec;54(12):5359-62.
2. Kim TS, et al. Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e02752-16.
3. Choi Y, et al. J Antimicrob Chemother. 2017 Oct 23. doi: 10.1093/jac/dkx367.
molnova catalog
related products
  • Sutezolid

    An oxazolidinone antibiotic that possesses potent antituberculosis activity in vitro and in vivo.

  • piperacillin

    Piperacillin is a semisynthetic penicillin with wide spectrum of antimicrobial activity(particularly pseudomonas strains.

  • DS86760016

    DS86760016 is a novel selective bacterial leucyl-tRNA synthetase (LeuRS) inhibitor with IC50 of 0.38 uM (Escherichia coli, LeuRS).