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Delavirdine
CAS No. 136817-59-9
Delavirdine ( U 90152;BHAP-U 90152 )
Catalog No. M11519 CAS No. 136817-59-9
A potent HIV-1 reverse transcriptase inhibitor with IC50 of 0.26 uM for recombinant HIV-1 RT.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameDelavirdine
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NoteResearch use only, not for human use.
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Brief DescriptionA potent HIV-1 reverse transcriptase inhibitor with IC50 of 0.26 uM for recombinant HIV-1 RT.
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DescriptionA potent HIV-1 reverse transcriptase inhibitor with IC50 of 0.26 uM for recombinant HIV-1 RT; exhibits IC50>440 uM for DNA polymerases α and δ; blocks the replication in peripheral blood lymphocytes of 25 primary HIV-1 isolates and has low cellular cytotoxicity; retains significant activity against mutant RTs (K103N, Y181C).HIV Infection Approved
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SynonymsU 90152;BHAP-U 90152
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV
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Research AreaInfection
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IndicationHIV Infection
Chemical Information
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CAS Number136817-59-9
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Formula Weight456.56
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Molecular FormulaC22H28N6O3S
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCC(C)NC1=C(N=CC=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)NS(=O)(=O)C
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Chemical NameMethanesulfonamide, N-[2-[[4-[3-[(1-methylethyl)amino]-2-pyridinyl]-1-piperazinyl]carbonyl]-1H-indol-5-yl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Dueweke TJ, et al. Antimicrob Agents Chemother. 1993 May;37(5):1127-31.
2. Romero DL, et al. J Med Chem. 1993 May 14;36(10):1505-8.
3. Olmsted RA, et al. J Virol. 1996 Jun;70(6):3698-705.
2. Romero DL, et al. J Med Chem. 1993 May 14;36(10):1505-8.
3. Olmsted RA, et al. J Virol. 1996 Jun;70(6):3698-705.
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