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Darunavir
CAS No. 206361-99-1
Darunavir ( TMC-114;UIC-94017 )
Catalog No. M13207 CAS No. 206361-99-1
A potent, selective HIV-1 protease inhibitor that is extremely potent against laboratory HIV-1 strains and primary clinical isolates with IC50 of 3 nM, IC90 of 9 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 36 | In Stock |
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| 10MG | 51 | In Stock |
|
| 50MG | 124 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameDarunavir
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective HIV-1 protease inhibitor that is extremely potent against laboratory HIV-1 strains and primary clinical isolates with IC50 of 3 nM, IC90 of 9 nM.
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DescriptionA potent, selective HIV-1 protease inhibitor that is extremely potent against laboratory HIV-1 strains and primary clinical isolates with IC50 of 3 nM, IC90 of 9 nM; blockes the infectivity and replication of HIV-1(NL4-3) variants with IC50 of 3-29 nM, also potent against multi-PI-resistant clinical HIV-1 variants isolated from patients; used to treat and prevent HIV/AIDS.HIV Infection Approved
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SynonymsTMC-114;UIC-94017
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIVProtease
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Research AreaInfection
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IndicationHIV Infection
Chemical Information
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CAS Number206361-99-1
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Formula Weight547.66
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Molecular FormulaC27H37N3O7S
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCC(C)CN(C[C@H]([C@H](CC1=CC=CC=C1)NC(=O)O[C@H]2CO[C@@H]3[C@H]2CCO3)O)S(=O)(=O)C4=CC=C(C=C4)N
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Chemical NameCarbamic acid, N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ester
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Surleraux DL, et al. J Med Chem. 2005 Mar 24;48(6):1813-22.
2. Koh Y, et al. Antimicrob Agents Chemother. 2003 Oct;47(10):3123-9.
3. King NM, et al. J Virol. 2004 Nov;78(21):12012-21.
2. Koh Y, et al. Antimicrob Agents Chemother. 2003 Oct;47(10):3123-9.
3. King NM, et al. J Virol. 2004 Nov;78(21):12012-21.
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