Daptomycin ( Cubicin; LY146032 )

Catalog No. M10148 CAS No. 103060-53-3

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Product Name

Daptomycin
Note

Research use only, not for human use.
Brief Description

Daptomycin is a novel antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.
Description

Daptomycin is a novel antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.
Synonyms

Cubicin; LY146032
Pathway

Cell Cycle/DNA Damage
Target

DNA/RNA Synthesis
Recptor

DNA synthesis
Research Area

Infection
Indication

——

CAS Number

103060-53-3
Formula Weight

1620.68
Molecular Formula

C72H101N17O26
Purity

>98%(HPLC)
Solubility

Water: 100 mg/mL (61.7 mM)
SMILES

O=C1NCC(N[C@@H](CCCN)C(N[C@@H](CC(O)=O)C(N[C@H](C)C(N[C@@H](CC(O)=O)C(NCC(N[C@H](CO)C(N[C@@H]([C@H](C)CC(O)=O)C(N[C@@H](CC(C2=CC=CC=C2N)=O)C(OC(C)C1NC([C@@H](NC([C@@H](NC([C@@H](NC(CCCCCCCCC)=O)CC3=CNC4=C3C=CC=C4)=O)CC(N)=O)=O)CC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Chemical Name

2,2'-((3S,6S,9R,15S,18R,21S,24S)-30-((S)-2-((S)-4-amino-2-((S)-2-decanamido-3-(1H-indol-3-yl)propanamido)-4-oxobutanamido)-3-carboxypropanamido)-3-(2-(2-aminophenyl)-2-oxoethyl)-24-(3-aminopropyl)-6-((R)-1-carboxypropan-2-yl)-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontane-15,21-diyl)diacetic acid

1. Silverman JA, et al. Antimicrob Agents ChemOthers, 2003, 47(8), 2538-2544.

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