DS08210767

CAS No. 2376334-75-5

DS08210767( —— )

Catalog No. M32894 CAS No. 2376334-75-5

DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with an IC50 of 90 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 196 Get Quote
5MG 306 Get Quote
10MG 443 Get Quote
25MG 638 Get Quote
50MG 878 Get Quote
100MG 1170 Get Quote
500MG 2349 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    DS08210767
  • Note
    Research use only, not for human use.
  • Brief Description
    DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with an IC50 of 90 nM.
  • Description
    DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with IC50 of 90 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    THR
  • Recptor
    Thyroid hormone receptor(THR)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2376334-75-5
  • Formula Weight
    513.67
  • Molecular Formula
    C31H39N5O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 5 mg/mL (9.73 mM; Ultrasonic (<80°C)
  • SMILES
    CC1(C)N=C(C2CCCCC2)c2ccc(cc2N(c2ccc(NCCNC3CCOCC3)cc2)C1=O)C#N
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Arai Y, et al. Discovery of novel PTHR1 antagonists: Design, synthesis, and structure activity relationships. Bioorg Med Chem Lett. 2019 Sep 15;29(18):2613-2616.?
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