
DS-1040
CAS No. 1335138-62-9
DS-1040( DS 1040 | DS1040 )
Catalog No. M11339 CAS No. 1335138-62-9
DS-1040 (DS1040)?is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa.
Purity : >98% (HPLC)






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Biological Information
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Product NameDS-1040
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NoteResearch use only, not for human use.
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Brief DescriptionDS-1040 (DS1040)?is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa.
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DescriptionDS-1040 (DS1040)?is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa; a novel fibrinolysis-enhancing agent has favorable pharmacokinetic/pharmacodynamic properties and a favorable safety profile.Stroke, Phase 2 Clinical.
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In Vitro——
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In Vivo——
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SynonymsDS 1040 | DS1040
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PathwayOthers
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TargetOther Targets
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RecptorOther Targets
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Research AreaNeurological Disease
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IndicationStroke
Chemical Information
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CAS Number1335138-62-9
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Formula Weight293.411
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Molecular FormulaC16H27N3O2
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(2S)-5-Amino-2-[[1-(trans-4-methylcyclohexyl)-1H-imidazol-4-yl]methyl]valeric acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zhou J, et al. J Thromb Haemost. 2017 May;15(5):961-971.
2. Gurewich V, et al. J Thromb Haemost. 2017 Oct;15(10):2080-2081.
3. Paul A Lapchak, et al. Abstract WP282: DS-1040 an Inhibitor of the Activated Thrombin Activatable Fibrinolysis Inhibitor Improves Behavior in Embolized Rabbits, Stroke. 2016;47:AWP282.
molnova catalog



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