Cart
sales@molnova.com
Home - Products - Microbiology/Virology - HIV - DPC-681

DPC-681

CAS No. 284661-68-3

DPC-681( DPH-153893 )

Catalog No. M13867 CAS No. 284661-68-3

A potent and selective inhibitor of HIV-1 protease with IC90 of 4-40 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 514 Get Quote
50MG 1962 Get Quote
100MG 2520 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    DPC-681
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent and selective inhibitor of HIV-1 protease with IC90 of 4-40 nM.
  • Description
    A potent and selective inhibitor of HIV-1 protease with IC90 of 4-40 nM; showes no loss in potency towardrecombinant mutant HIVs with the D30N mutation and a fivefold or smaller loss in potency toward mutant variants with three to five amino acid substitutions.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    DPH-153893
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    HIV
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    284661-68-3
  • Formula Weight
    669.8495
  • Molecular Formula
    C35H48FN5O5S
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    CC(C)(C)[C@@H](C(N)=O)N(C(CNCC1=CC=CC(F)=C1)=O)[C@@H](CC2=CC=CC=C2)[C@H](O)CN(S(=O)(C3=CC=CC(N)=C3)=O)CC(C)C
  • Chemical Name
    L-Valinamide, N-[(3-fluorophenyl)methyl]glycyl-N-[(1S,2R)-3-[[(3-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-3-methyl-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kaltenbach RF 3rd, et al. Antimicrob Agents Chemother. 2001 Nov;45(11):3021-8. 2. Solon EG, et al. Drug Metab Dispos. 2002 Nov;30(11):1164-9.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • 3-Deazaadenosine hyd...

    3-Deazaadenosine hydrochloride is an inhibitor of S-adenosylhomocysteine hydrolase (Ki: 3.9 μM). It has anti-inflammatory, anti-proliferative, and anti-HIV activity.3-Deazaadenosine shows the anti-HIV effect and inhibits p24 antigen in peripheral blood mononuclear (PBMCs) cells infected with HIV-1 isolates (A012 and A018, IC50s: 0.15 and 0.20 μM).

  • Apelin-36 (human)

    Endogenous APJ receptor agonist (EC50 = 20 nM) that is secreted by adipocytes. Binds with high affinity to human APJ receptors expressed in HEK 293 cells (pIC50= 8.61). Involved in regulation of cardiovascular function, fluid homeostasis and feeding. Blocks entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ.

  • Nef-IN-B9

    Nef-IN-B9 (Nef inhibitor B9) is a small molecule that blocks Nef-dependent Hck activity with IC50 of 2.8 uM.

Sign In Join Free