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DNS-pE
CAS No. 2196245-98-2
DNS-pE( PHGDH Fluorescent Probe DNS-pE )
Catalog No. M13501 CAS No. 2196245-98-2
DNS-pE (PHGDH Fluorescent Probe DNS-pE) is the first small molecule that can selectively label endogenous 3-phosphoglycerate dehydrogenase (PHGDH) from various mammalian cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
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| 50MG | 1782 | Get Quote |
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| 100MG | 2250 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameDNS-pE
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NoteResearch use only, not for human use.
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Brief DescriptionDNS-pE (PHGDH Fluorescent Probe DNS-pE) is the first small molecule that can selectively label endogenous 3-phosphoglycerate dehydrogenase (PHGDH) from various mammalian cells.
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DescriptionDNS-pE (PHGDH Fluorescent Probe DNS-pE) is the first small molecule that can selectively label endogenous 3-phosphoglycerate dehydrogenase (PHGDH) from various mammalian cells; is highly fluorescent only upon irreversible covalent modification of PHGDH with an inhibitory property (in vitro Ki=7.4 uM).
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In Vitro——
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In Vivo——
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SynonymsPHGDH Fluorescent Probe DNS-pE
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PathwayOthers
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TargetFluorescent Dye
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RecptorFluorescent Dye
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Research Area——
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Indication——
Chemical Information
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CAS Number2196245-98-2
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Formula Weight261.339
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Molecular FormulaC14H15NO2S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=S(C1=CC2=CC=C(N(C)C)C=C2C=C1)(C=C)=O
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Chemical NameN,N-dimethyl-6-(vinylsulfonyl)naphthalen-2-amine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Pan S, et al. Angew Chem Int Ed Engl. 2018 Jan 8;57(2):579-583.
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