DL-Buthionine-(SR)-sulfoximine
CAS No. 5072-26-4
DL-Buthionine-(SR)-sulfoximine ( Butionine sulfoximine;NSC 381100 )
Catalog No. M20963 CAS No. 5072-26-4
DL-Buthionine-(SR)-sulfoximine is an inhibitor of γ-glutamylcysteine synthetase?for the treatment of solid tumors.
Purity : >98% (HPLC)
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Biological Information
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Product NameDL-Buthionine-(SR)-sulfoximine
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NoteResearch use only not for human use.
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Brief DescriptionDL-Buthionine-(SR)-sulfoximine is an inhibitor of γ-glutamylcysteine synthetase?for the treatment of solid tumors.
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DescriptionDL-Buthionine-(SR)-sulfoximine is an inhibitor of γ-glutamylcysteine synthetase?for the treatment of solid tumors.
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SynonymsButionine sulfoximine;NSC 381100
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PathwayOthers
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TargetOther Targets
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Recptorγ-glutamylcysteine synthetase
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Research Area——
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Indication——
Chemical Information
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CAS Number5072-26-4
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Formula Weight222.31
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Molecular FormulaC8H18N2O3S
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Purity>98% (HPLC)
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SolubilityH2O:41.67 mg/mL (187.44 mM; Need ultrasonic)
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SMILESCCCCS(=N)(=O)CCC(N)C(=O)O
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Chemical Name2-amino-4-(butylsulfonimidoyl)butanoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Verdiperstat
Verdiperstat (AZD-3241) is a potent, selective, reversible, orally active myeloperoxidase (MPO) inhibitor with IC50 of 630 nM, >14-fold selectivity over thyroid peroxidase (TPO).
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A-71915 TFA (132956-...
A-71915 (TFA) is a selective inhibitor of ANP receptor (atrial natriuretic peptide-receptor), induces apoptosis and decreases insulin secretion in RINm5F pancreatic β-cells.
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Urantide
Selective and competitive urotensin-II (UT) receptor antagonist (pKB = 8.3). Blocks hU-II induced contractions in thoracic aorta ex vivo. Exhibits no effect on noradrenaline or endothelin 1-induced contraction or on acetylcholine-induced relaxation. Behaves as a partial agonist in a calcium mobilization assay (in CHO cells expressing hUT receptors).