Cart
sales@molnova.com
Necroptosis-IN-3
CAS No. 547698-18-0
Necroptosis-IN-3( —— )
Catalog No. M35795 CAS No. 547698-18-0
Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis. Necroptosis-IN-3 (Compound STX1638) also inhibits 11β-HSD1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 55 | In Stock |
|
| 10MG | 98 | In Stock |
|
| 25MG | 191 | In Stock |
|
| 50MG | 297 | In Stock |
|
| 100MG | 420 | In Stock |
|
| 200MG | 583 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameNecroptosis-IN-3
-
NoteResearch use only, not for human use.
-
Brief DescriptionNecroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis. Necroptosis-IN-3 (Compound STX1638) also inhibits 11β-HSD1.
-
DescriptionNecroptosis-IN-3 (Compound 69) is a necroptosis inhibitor that inhibits TNF-α induced necroptosis. Necroptosis-IN-3 (Compound STX1638) also inhibits 11β-HSD1.
-
In VitroCell Viability Assay Cell Line:Fadd-/- Jurkat and L929 cells, treated with 10 ng/mL of human TNF-α Concentration:0.030-100 μM Incubation Time:24 h Result:Showed necroptosis inhibitory activity with an ED50 of 7.724 μM for Fadd-/- Jurkat cells and was inactive for L929 cells.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorNecroptosis
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number547698-18-0
-
Formula Weight223.33
-
Molecular FormulaC12H17NOS
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (447.77 mM; Ultrasonic )
-
SMILESC(NCC1=CC=CS1)(=O)C2CCCCC2
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Junying Yuan, et al. Small molecule inhibitors of necroptosis. Patent US20120122889A1.
molnova catalog
related products
-
Protease K
Protease K is a nonspecific serine protease that is useful for general digestion of proteins.?It is active in the presence of SDS or urea and over a wide range of pH (4-12), salt concentrations, and temperatures.
-
Glycerophospholipids...
Glycerophospholipids, cephalins (Phosphatidylethanolamines (egg)) are a mixture of phosphatidylethanolamines isolated from eggs, with various fatty acyl groups at the sn-1 and sn-2 positions.
-
Arecaidine hydrochlo...
Arecaidine hydrochloride may have carcinogenesis.
