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DGY-06-116

CAS No. ——

DGY-06-116( —— )

Catalog No. M22645 CAS No. ——

DGY-06-116 is an selective and irreversible covalent inhibitor of Src and FGFR1 with IC50 value of 3nM and 8340 nM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    DGY-06-116
  • Note
    Research use only, not for human use.
  • Brief Description
    DGY-06-116 is an selective and irreversible covalent inhibitor of Src and FGFR1 with IC50 value of 3nM and 8340 nM, respectively.
  • Description
    DGY-06-116 is an selective and irreversible covalent inhibitor of Src and FGFR1 with IC50 value of 3nM and 8340 nM, respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Tyrosine Kinase
  • Target
    Src
  • Recptor
    Src|FGFR1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    ——
  • Formula Weight
    597.11
  • Molecular Formula
    C32H33ClN8O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL (167.47 mM)
  • SMILES
    CN1CCN(CC1)c1ccc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)c(Nc3ccccc3NC(=O)C=C)n2)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Gurbani D , Du G , Henning N J , et al. Structure and Characterization of a Covalent Inhibitor of Src Kinase[J]. Frontiers in Molecular Bioences, 2020, 7:81.
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