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DFP00173

CAS No. 672286-03-2

DFP00173( —— )

Catalog No. M26152 CAS No. 672286-03-2

DFP00173 is a potent and selective aquaporin 3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with IC50 of ~0.1-0.4 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    DFP00173
  • Note
    Research use only, not for human use.
  • Brief Description
    DFP00173 is a potent and selective aquaporin 3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with IC50 of ~0.1-0.4 μM.
  • Description
    DFP00173 is a potent and selective aquaporin 3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with IC50 of ~0.1-0.4 μM. Compared with the homologous AQP subtypes AQP7 and AQP9, DFP00173 is selective for AQP3.(In Vitro):DFP00173 inhibits the glycerol permeability of human red blood cells with IC50 of ~0.2 μM.
  • In Vitro
    DFP00173 inhibits the glycerol permeability of human erythrocytes with an IC50 of ~0.2 μM.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    672286-03-2
  • Formula Weight
    332.16
  • Molecular Formula
    C11H7Cl2N3O3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 100 mg/mL (301.06 mM)
  • SMILES
    [O-][N+](=O)c1cc(NC(=O)Nc2c(Cl)cccc2Cl)cs1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.S Moein Moghimi, et al. Allergic Reactions and Anaphylaxis to LNP-Based COVID-19 Vaccines. Mol Ther. 2021 Mar 3;29(3):898-900.
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