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DFP00173

CAS No. 672286-03-2

DFP00173( —— )

Catalog No. M26152 CAS No. 672286-03-2

DFP00173 is a potent and selective aquaporin 3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with IC50 of ~0.1-0.4 μM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

DFP00173
Note

Research use only, not for human use.
Brief Description

DFP00173 is a potent and selective aquaporin 3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with IC50 of ~0.1-0.4 μM.
Description

DFP00173 is a potent and selective aquaporin 3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with IC50 of ~0.1-0.4 μM. Compared with the homologous AQP subtypes AQP7 and AQP9, DFP00173 is selective for AQP3.(In Vitro):DFP00173 inhibits the glycerol permeability of human red blood cells with IC50 of ~0.2 μM.
In Vitro

DFP00173 inhibits the glycerol permeability of human erythrocytes with an IC50 of ~0.2 μM.
In Vivo

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Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

——
Research Area

——
Indication

——

Chemical Information

CAS Number

672286-03-2
Formula Weight

332.16
Molecular Formula

C11H7Cl2N3O3S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : ≥ 100 mg/mL (301.06 mM)
SMILES

[O-][N+](=O)c1cc(NC(=O)Nc2c(Cl)cccc2Cl)cs1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.S Moein Moghimi, et al. Allergic Reactions and Anaphylaxis to LNP-Based COVID-19 Vaccines. Mol Ther. 2021 Mar 3;29(3):898-900.

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