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DEL-22379
CAS No. 181223-80-3
DEL-22379 ( DEL22379;DEL 22379 )
Catalog No. M12782 CAS No. 181223-80-3
A small molecule inhibitor of ERK dimerization with IC50 of 0.5 uM, without affecting ERK phosphorylation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 39 | In Stock |
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| 5MG | 61 | In Stock |
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| 10MG | 113 | In Stock |
|
| 25MG | 207 | In Stock |
|
| 50MG | 332 | In Stock |
|
| 100MG | 494 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDEL-22379
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NoteResearch use only, not for human use.
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Brief DescriptionA small molecule inhibitor of ERK dimerization with IC50 of 0.5 uM, without affecting ERK phosphorylation.
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DescriptionA small molecule inhibitor of ERK dimerization with IC50 of 0.5 uM, without affecting ERK phosphorylation; prevents tumorigenesis by RAS-ERK pathway oncogenes.
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SynonymsDEL22379;DEL 22379
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PathwayMAPK/ERK Signaling
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TargetERK
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RecptorERK
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number181223-80-3
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Formula Weight444.53
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Molecular FormulaC26H28N4O3
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 30 mg/mL
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SMILESO=C(NC1=CC2=C(NC(/C2=C/C3=CNC4=C3C=C(OC)C=C4)=O)C=C1)CCN5CCCCC5
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Chemical Name1-Piperidinepropanamide, N-[2,3-dihydro-3-[(5-methoxy-1H-indol-3-yl)methylene]-2-oxo-1H-indol-5-yl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Herrero A, et al. Cancer Cell. 2015 Aug 10;28(2):170-82.
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