DD1

CAS No. 187585-11-1

DD1( 3,3'-Diamino-4'-methoxyflavone | HUN85111 )

Catalog No. M23854 CAS No. 187585-11-1

DD1 is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 300 In Stock
10MG 509 In Stock
25MG 802 In Stock
50MG 1107 In Stock
100MG 1503 In Stock
500MG 3015 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    DD1
  • Note
    Research use only, not for human use.
  • Brief Description
    DD1 is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.
  • Description
    DD1 is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.
  • In Vitro
    DD1 (20 μM; 96 h) shows antiproliferation activity in a dose- and time-dependent manner in U937 cells.DD1 induces cell cycle arrest at G2/M phase and apoptosis.DD1 (10, 20 μM; 48 h) induces mitochondrial membrane depolarization, Bax upregulation and Bad dephosphorylation.DD1 (2-20 μM; 40 h) shows inhibitor for chymotrypsin-like activity in U937 lysates.
  • In Vivo
    ——
  • Synonyms
    3,3'-Diamino-4'-methoxyflavone | HUN85111
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Proteasome
  • Recptor
    proteasome
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    187585-11-1
  • Formula Weight
    282.29
  • Molecular Formula
    C16H14N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    COC1=C(C=C(C=C1)C2=C(C(=O)C3=CC=CC=C3O2)N)N
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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