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Cyclo(RGDyK)
CAS No. 250612-42-1
Cyclo(RGDyK) ( Cyclic Arg-Gly-Asp-D-Tyr-Lys )
Catalog No. M13737 CAS No. 250612-42-1
Cyclo(RGDyK) (Cyclic Arg-Gly-Asp-D-Tyr-Lys) is a cyclic derivative of RGD, potent, selective αVβ3 integrin inhibitor with IC50 of 20 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 80 | In Stock |
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| 10MG | 132 | In Stock |
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| 25MG | 267 | In Stock |
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| 50MG | 439 | In Stock |
|
| 100MG | 641 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameCyclo(RGDyK)
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NoteResearch use only, not for human use.
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Brief DescriptionCyclo(RGDyK) (Cyclic Arg-Gly-Asp-D-Tyr-Lys) is a cyclic derivative of RGD, potent, selective αVβ3 integrin inhibitor with IC50 of 20 nM.
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DescriptionCyclo(RGDyK) (Cyclic Arg-Gly-Asp-D-Tyr-Lys) is a cyclic derivative of RGD, potent, selective αVβ3 integrin inhibitor with IC50 of 20 nM; a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins including αvβ3.
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SynonymsCyclic Arg-Gly-Asp-D-Tyr-Lys
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PathwayCell Cycle/DNA Damage
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TargetIntegrin
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RecptorαVβ3integrin
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Research AreaCardiovascular Disease
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Indication——
Chemical Information
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CAS Number250612-42-1
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Formula Weight847.72
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Molecular FormulaC31H43F6N9O12
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Purity>98% (HPLC)
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SolubilityDMSO: 94 mg/mL (110.9 mM)Water: 94 mg/mL (110.9 mM) （ < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCN=C(N)N)CCCCN)CC2=CC=C(C=C2)O)CC(=O)O.C(=O)(C(F)(F)F)O.C(=O)(C(F)(F)F)O
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Chemical NameCyclo(L-arginylglycyl-L-α-aspartyl-D-tyrosyl-L-lysyl), bis(trifluoroacetate) (salt) (9CI)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Haubner R, et al. J Nucl Med. 2001 Feb;42(2):326-36.
2. Chen Y, et al. PLoS One. 2016 Mar 1;11(3):e0149952.
3. Guo L, et al. J Nanosci Nanotechnol. 2014 Jul;14(7):4858-64.
2. Chen Y, et al. PLoS One. 2016 Mar 1;11(3):e0149952.
3. Guo L, et al. J Nanosci Nanotechnol. 2014 Jul;14(7):4858-64.
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