Crebanine

CAS No. 25127-29-1

Crebanine ( Crebanine; Crebanin )

Catalog No. M18308 CAS No. 25127-29-1

Crebanine iv 5mg/kg can eonvert BaCl_2-induced arrhythmia into sinus rhythm in rats, and can significantly increase the tolerant dose of aconitine to produce ventrieular fibrillation(VF) and cardiac arrest (CA) in rata.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 86 In Stock
10MG 149 In Stock
25MG 287 In Stock
50MG 431 In Stock
100MG 619 In Stock
500MG 1278 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Crebanine
  • Note
    Research use only, not for human use.
  • Brief Description
    Crebanine iv 5mg/kg can eonvert BaCl_2-induced arrhythmia into sinus rhythm in rats, and can significantly increase the tolerant dose of aconitine to produce ventrieular fibrillation(VF) and cardiac arrest (CA) in rata.
  • Description
    Crebanine iv 5mg/kg can eonvert BaCl_2-induced arrhythmia into sinus rhythm in rats, and can significantly increase the tolerant dose of aconitine to produce ventrieular fibrillation(VF) and cardiac arrest (CA) in rata. Crebanine can also decrease the incidence of VF and CA by CaCl_2 in rats and by chloroform in mice, but has no proteetive effects on ouahain-indueed arrhythmias in guinea pigs. Crebanine has potential utility of crebanine in the development of neurodegenerative therapy, might be used as the starting point to develop a drug for Alzheimer's disease. Crebanine has anti-cancer activity, can inhibit the proliferation of human leukemic cells (HL-6, U937 and K562), human fibrosarcoma cells (HT18) and cervix cancer cell lines (KB-3-1 and KB-V1; it mediates cell cycle arrest at G/G1 phase and this was associated with down-regulation of cyclins A and D.
  • Synonyms
    Crebanine; Crebanin
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Others
  • Research Area
    Cancer|Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    25127-29-1
  • Formula Weight
    339.39
  • Molecular Formula
    C20H21NO4
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    CN1CCC2=CC3=C(C4=C2C1CC5=C4C=CC(=C5OC)OC)OCO3
  • Chemical Name
    5H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinoline, 6,7,7a,8-tetrahydro-9,10-dimethoxy-7-methyl-, (R)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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