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Clozic

CAS No. 22494-47-9

Clozic ( ICI 55897; Clobuzarit )

Catalog No. M26122 CAS No. 22494-47-9

Clozic exhibits reversible anti-proliferative effects and can be used in studies about serving as a potential anti-arthritic agent.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Clozic
  • Note
    Research use only, not for human use.
  • Brief Description
    Clozic exhibits reversible anti-proliferative effects and can be used in studies about serving as a potential anti-arthritic agent.
  • Description
    Clozic exhibits reversible anti-proliferative effects and can be used in studies about serving as a potential anti-arthritic agent.(In Vitro):Clozic (>50 μM) dose-dependently decreases the amount of matrix protein synthesized by RHMC cell cultures. Clozic dose-dependently inhibits RHMC cell culture growth. Clozic (500 μM) does not affect Lactate dehydrogenase levels.
  • Synonyms
    ICI 55897; Clobuzarit
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    MTH1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    22494-47-9
  • Formula Weight
    304.8
  • Molecular Formula
    C17H17ClO3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)(OCc1ccc(cc1)-c1ccc(Cl)cc1)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.In vitro antiplasmodial activity of benzophenones and xanthones from edible fruits of Garcinia species. Planta Med. 2014 Jun;80(8-9):676-81.
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