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Clozapine

CAS No. 5786-21-0

Clozapine( HF 1854 )

Catalog No. M15120 CAS No. 5786-21-0

An atypical antipsychotic agent that binds to 5-HT and dopamine receptor; is also potent at the α2-adrenoceptor with Ki of 51 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
50MG 58 In Stock
100MG 87 In Stock
200MG 156 In Stock
500MG 286 In Stock
1G 426 In Stock
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Biological Information

  • Product Name
    Clozapine
  • Note
    Research use only, not for human use.
  • Brief Description
    An atypical antipsychotic agent that binds to 5-HT and dopamine receptor; is also potent at the α2-adrenoceptor with Ki of 51 nM.
  • Description
    An atypical antipsychotic agent that binds to 5-HT and dopamine receptor; is also potent at the α2-adrenoceptor with Ki of 51 nM; mainly used for schizophrenia.Schizophrenia Approved.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    HF 1854
  • Pathway
    GPCR/G Protein
  • Target
    Dopamine Receptor
  • Recptor
    D2|M1mAChR|α2-adrenoceptor
  • Research Area
    Neurological Disease
  • Indication
    Schizophrenia

Chemical Information

  • CAS Number
    5786-21-0
  • Formula Weight
    326.8233
  • Molecular Formula
    C18H19ClN4
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    CN1CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl
  • Chemical Name
    5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-1-piperazinyl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Seeman P, et al. ACS Chem Neurosci. 2014 Jan 15;5(1):24-9. 2. Zhukovskaya NL, et al. Neurosci Lett. 2000 Jul 21;288(3):236-40. 3. Moreno JL, et al. Psychopharmacology (Berl). 2013 Jan;225(1):217-26.
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