Cart
sales@molnova.com
Clozapine
CAS No. 5786-21-0
Clozapine( HF 1854 )
Catalog No. M15120 CAS No. 5786-21-0
An atypical antipsychotic agent that binds to 5-HT and dopamine receptor; is also potent at the α2-adrenoceptor with Ki of 51 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 58 | In Stock |
|
| 100MG | 87 | In Stock |
|
| 200MG | 156 | In Stock |
|
| 500MG | 286 | In Stock |
|
| 1G | 426 | In Stock |
|
Biological Information
-
Product NameClozapine
-
NoteResearch use only, not for human use.
-
Brief DescriptionAn atypical antipsychotic agent that binds to 5-HT and dopamine receptor; is also potent at the α2-adrenoceptor with Ki of 51 nM.
-
DescriptionAn atypical antipsychotic agent that binds to 5-HT and dopamine receptor; is also potent at the α2-adrenoceptor with Ki of 51 nM; mainly used for schizophrenia.Schizophrenia Approved.
-
In Vitro——
-
In Vivo——
-
SynonymsHF 1854
-
PathwayGPCR/G Protein
-
TargetDopamine Receptor
-
RecptorD2|M1mAChR|α2-adrenoceptor
-
Research AreaNeurological Disease
-
IndicationSchizophrenia
Chemical Information
-
CAS Number5786-21-0
-
Formula Weight326.8233
-
Molecular FormulaC18H19ClN4
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESCN1CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl
-
Chemical Name5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-1-piperazinyl)-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Seeman P, et al. ACS Chem Neurosci. 2014 Jan 15;5(1):24-9.
2. Zhukovskaya NL, et al. Neurosci Lett. 2000 Jul 21;288(3):236-40.
3. Moreno JL, et al. Psychopharmacology (Berl). 2013 Jan;225(1):217-26.
molnova catalog
related products
-
2'-O-Methylisoliquir...
2'-O-Methylisoliquiritigenin, a compound synthesized by enzymes specifically induced in NR.2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-regulates 5-HT, NE, DA and GABA pathways.
-
JNJ-37822681
JNJ-37822681 is a novel, highly selective dopamine D? receptor antagonist characterized by a rapid dissociation rate from the dopamine D? receptor.
-
Ordopidine
Ordopidine (ACR325) is a dopaminergic stabilizer that suppresses psychostimulant-induced hyperactivity disorder and stimulates behavior during inactivity.
