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Cligosiban
CAS No. 900510-03-4
Cligosiban( PF-3274167 | PF 03274167 )
Catalog No. M16474 CAS No. 900510-03-4
A potent, specific oxytocin receptor antagonist with Ki of 9.5 nM, displays high selectivity over the vasopressin receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 42 | In Stock |
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| 10MG | 68 | In Stock |
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| 25MG | 143 | In Stock |
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| 50MG | 230 | In Stock |
|
| 100MG | 370 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCligosiban
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, specific oxytocin receptor antagonist with Ki of 9.5 nM, displays high selectivity over the vasopressin receptors.
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DescriptionA potent, specific oxytocin receptor antagonist with Ki of 9.5 nM, displays high selectivity over the vasopressin receptors; demonstrates excellent potency and selectivity, as well as promising in vivo pharmacokinetics and significantly improved aqueous solubility.Sexual Dysfunction Phase 1 Discontinued.
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In Vitro——
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In Vivo——
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SynonymsPF-3274167 | PF 03274167
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PathwayGPCR/G Protein
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TargetOXTR
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RecptorOXTR
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Research AreaEndocrinology
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IndicationSexual Dysfunction
Chemical Information
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CAS Number900510-03-4
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Formula Weight419.841
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Molecular FormulaC19H19ClFN5O3
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Purity>98% (HPLC)
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SolubilityDMSO: Soluble （ < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESCOC1=NC=C(N2C(N3CC(OC4=CC=C(F)C=C4Cl)C3)=NN=C2COC)C=C1
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Chemical Name5-(3-(3-(2-chloro-4-fluorophenoxy)azetidin-1-yl)-5-(methoxymethyl)-4H-1,2,4-triazol-4-yl)-2-methoxypyridine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Vidal B, et al. Nucl Med Biol. 2017 Dec;55:1-6.
2. Brown A, et al. Bioorg Med Chem Lett. 2010 Jan 15;20(2):516-20.
molnova catalog
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Cligosiban
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