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Cisplatin

CAS No. 15663-27-1

Cisplatin ( CDDP;cis-Diaminodichloroplatinum )

Catalog No. M12235 CAS No. 15663-27-1

A chemotherapy agent that interferes with DNA replication and kills cancer cells; induces growth arrest and/or apoptosis in most cancer cell types; an alkylating agent for treatment of a number of cancers.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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100MG 38 In Stock
500MG 87 In Stock
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Biological Information

  • Product Name
    Cisplatin
  • Note
    Research use only, not for human use.
  • Brief Description
    A chemotherapy agent that interferes with DNA replication and kills cancer cells; induces growth arrest and/or apoptosis in most cancer cell types; an alkylating agent for treatment of a number of cancers.
  • Description
    A chemotherapy agent that interferes with DNA replication and kills cancer cells; induces growth arrest and/or apoptosis in most cancer cell types; an alkylating agent for treatment of a number of cancers.Chemotherapeutic Agents Approved
  • Synonyms
    CDDP;cis-Diaminodichloroplatinum
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA Alkylator
  • Recptor
    Caspase-3; Caspase-9
  • Research Area
    Cancer
  • Indication
    Chemotherapeutic

Chemical Information

  • CAS Number
    15663-27-1
  • Formula Weight
    300.05
  • Molecular Formula
    Cl2H6N2Pt
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 31 mg/mL (DMSO can inactivate Cisplatin's activity)
  • SMILES
    Cl[Pt-2]([NH3+])([NH3+])Cl
  • Chemical Name
    Platinum, diamminedichloro-, (SP-4-2)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wang X, et al. J Biol Chem. 2000 Dec 15;275(50):39435-43.
2. Cummings BS, et al. J Pharmacol Exp Ther. 2002 Jul;302(1):8-17.
3. Hall MD, et al. Cancer Res. 2014 Jul 15;74(14):3913-22.
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