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Alchemix
CAS No. 281189-60-4
Alchemix ( ZP281M )
Catalog No. M13856 CAS No. 281189-60-4
A dual action as an alkylating agent and topoisomerase inhibitor with potent activity against anthracycline- and cisplatin-resistant tumor cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameAlchemix
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NoteResearch use only, not for human use.
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Brief DescriptionA dual action as an alkylating agent and topoisomerase inhibitor with potent activity against anthracycline- and cisplatin-resistant tumor cancer.
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DescriptionA dual action as an alkylating agent and topoisomerase inhibitor with potent activity against anthracycline- and cisplatin-resistant tumor cancer; shows excellent antitumor activity in Adriamycin-resistant (2780AD) and cisplatin-resistant cell lines (IC50=19 nM) in vitro and in vivo; induces cell death independently of ATM and p53.
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SynonymsZP281M
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PathwayCell Cycle/DNA Damage
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TargetDNA Alkylator
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RecptorDNA Alkylator
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Research Area——
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Indication——
Chemical Information
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CAS Number281189-60-4
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Formula Weight509.43
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Molecular FormulaC24H30Cl2N4O4
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name1-((2-(bis(2-chloroethyl)amino)ethyl)amino)-4-((2-(dimethylamino)ethyl)amino)-5,8-dihydroxyanthracene-9,10-dione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Pors K, et al. Mol Cancer Ther. 2003 Jul;2(7):607-10.
2. Pors K, et al. J Med Chem. 2004 Mar 25;47(7):1856-9.
3. Thomas A, et al. Oncogene. 2015 Jun;34(25):3336-48.
2. Pors K, et al. J Med Chem. 2004 Mar 25;47(7):1856-9.
3. Thomas A, et al. Oncogene. 2015 Jun;34(25):3336-48.
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