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Cisapride

CAS No. 81098-60-4

Cisapride( Kaudalit | Kinestase | Prepulsid | Presid | Pridesia | Propulsid )

Catalog No. M16029 CAS No. 81098-60-4

Cisapride is a gastroprokinetic agent, a drug that increases motility in the upper gastrointestinal tract.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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50MG 90 In Stock
100MG 123 In Stock
200MG 222 In Stock
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Biological Information

  • Product Name
    Cisapride
  • Note
    Research use only, not for human use.
  • Brief Description
    Cisapride is a gastroprokinetic agent, a drug that increases motility in the upper gastrointestinal tract.
  • Description
    Cisapride is a gastroprokinetic agent, a drug that increases motility in the upper gastrointestinal tract. It acts directly as a serotonin 5-HT4 receptor agonist and indirectly as a parasympathomimetic. Stimulation of the serotonin receptors increases acetylcholine release in the enteric nervous system.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male Wistar rats with trinitrobenzenesulfonic-acid-(TNBS) induced rat colitis Dosage:2 mg/kg (i.p.); 4 mg/kg, (oral administration)Administration:2 mg/kg, intraperitoneal injection ; 4 mg/kg, oral administration; once Result:Showed severe and intense transmural inflammation and diffuse necrosis, inflammatory granulomas and submucosal neutrophils infiltration in colitis rat. Induced body weight loss.
  • Synonyms
    Kaudalit | Kinestase | Prepulsid | Presid | Pridesia | Propulsid
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HT| Potassium Channel
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    81098-60-4
  • Formula Weight
    465.95
  • Molecular Formula
    C23H29ClFN3O4
  • Purity
    >98% (HPLC)
  • Solubility
    Water: 2.71 mg/L
  • SMILES
    O=C(N[C@H]1[C@@H](OC)CN(CCCOC2=CC=C(F)C=C2)CC1)C3=CC(Cl)=C(N)C=C3OC
  • Chemical Name
    Benzamide, 4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-3-methoxy-4-piperidinyl)-2-methoxy-, cis-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Nagakura Y, et al. Pharmacol Res. 1999 May;39(5):375-82.
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