Cisapride ( Kaudalit; Kinestase; Prepulsid; Presid; Pridesia; Propulsid )

Catalog No. M16029 CAS No. 81098-60-4

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Product Name

Cisapride
Note

Research use only, not for human use.
Brief Description

Cisapride is a gastroprokinetic agent, a drug that increases motility in the upper gastrointestinal tract.
Description

Cisapride is a gastroprokinetic agent, a drug that increases motility in the upper gastrointestinal tract. It acts directly as a serotonin 5-HT4 receptor agonist and indirectly as a parasympathomimetic. Stimulation of the serotonin receptors increases acetylcholine release in the enteric nervous system.
Synonyms

Kaudalit; Kinestase; Prepulsid; Presid; Pridesia; Propulsid
Pathway

Endocrinology/Hormones
Target

5-HT Receptor
Recptor

5-HT; Potassium Channel
Research Area

Neurological Disease
Indication

——

CAS Number

81098-60-4
Formula Weight

465.95
Molecular Formula

C23H29ClFN3O4
Purity

>98%(HPLC)
Solubility

Water: 2.71 mg/L
SMILES

O=C(N[C@H]1[C@@H](OC)CN(CCCOC2=CC=C(F)C=C2)CC1)C3=CC(Cl)=C(N)C=C3OC
Chemical Name

Benzamide, 4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-3-methoxy-4-piperidinyl)-2-methoxy-, cis-

1.Nagakura Y, et al. Pharmacol Res. 1999 May;39(5):375-82.

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