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YL0919
CAS No. 1339058-04-6
YL0919 ( YL-0919;YL 0919 )
Catalog No. M11363 CAS No. 1339058-04-6
An orally active, dual 5-HT1A agonist and selective serotonin reuptake inhibitor with Ki of 0.19 nM and IC50 of 1.78 nM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 35 | In Stock |
|
| 5MG | 58 | In Stock |
|
| 10MG | 72 | In Stock |
|
| 25MG | 110 | In Stock |
|
| 50MG | 178 | In Stock |
|
| 100MG | 332 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameYL0919
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NoteResearch use only, not for human use.
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Brief DescriptionAn orally active, dual 5-HT1A agonist and selective serotonin reuptake inhibitor with Ki of 0.19 nM and IC50 of 1.78 nM, respectively.
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DescriptionAn orally active, dual 5-HT1A agonist and selective serotonin reuptake inhibitor with Ki of 0.19 nM and IC50 of 1.78 nM, respectively; shows no affinity for dopamine receptors and others 5-HT receptors; inhibits forskolin-stimulated cAMP formation and 5-HT uptake in both rat cortical synaptosomes and recombinant cells; significantly reverses the depressive-like behaviors in chronically stressed rats.
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SynonymsYL-0919;YL 0919
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor5-HT; 5-HT1A
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number1339058-04-6
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Formula Weight334.84
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Molecular FormulaC18H23ClN2O2
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 30 mg/mL
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SMILESO=C1C=CC=CN1CC2(O)CCN(CC3=CC=CC=C3)CC2.[H]Cl
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Chemical Name2(1H)-Pyridinone, 1-[[4-hydroxy-1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride (1:1)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chen HX, et al. PLoS One. 2013 Dec 18;8(12):e83271.
2. Zhang LM, et al. Br J Pharmacol. 2017 May;174(9):769-780.
3. Qin JJ, et al. Neurosci Lett. 2014 Oct 17;582:104-8.
2. Zhang LM, et al. Br J Pharmacol. 2017 May;174(9):769-780.
3. Qin JJ, et al. Neurosci Lett. 2014 Oct 17;582:104-8.
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