Tadalafil

CAS No. 171596-29-5

Tadalafil ( IC351, IC-351, IC 351, Tadalafil, Adcirca, Cialis )

Catalog No. M12614 CAS No. 171596-29-5

Tadalafil is a potent phosphodiesterase-5 (PDE5) inhibitor (IC50=1 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG 45 In Stock
50MG 66 In Stock
100MG 101 In Stock
200MG 169 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Tadalafil
  • Note
    Research use only, not for human use.
  • Brief Description
    Tadalafil is a potent phosphodiesterase-5 (PDE5) inhibitor (IC50=1 nM).
  • Description
    Tadalafil is a potent phosphodiesterase-5 (PDE5) inhibitor (IC50=1 nM); no inhibition on most of the other families of PDEs, with the exception of PDE11.Sexual Dysfunction Approved
  • Synonyms
    IC351, IC-351, IC 351, Tadalafil, Adcirca, Cialis
  • Pathway
    Angiogenesis
  • Target
    PDE
  • Recptor
    PDE5
  • Research Area
    Endocrinology
  • Indication
    Sexual Dysfunction

Chemical Information

  • CAS Number
    171596-29-5
  • Formula Weight
    389.40
  • Molecular Formula
    C22H19N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 52 mg/mL
  • SMILES
    O=C([C@@]1([H])CC2=C([C@@H](C3=CC(OCO4)=C4C=C3)N15)NC6=C2C=CC=C6)N(C)CC5=O
  • Chemical Name
    Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Blount MA, et al. Mol Pharmacol, 2004, 66(1), 144-152.
2. Ring BJ, et al. Clin Pharmacol Ther, 2005, 77(1), 63-75.
molnova catalog
related products
  • Sildenafil

    Sildenfail is a vasoactive agent used to treat erectile dysfunction and reduce symptoms in patients with pulmonary arterial hypertension (PAH).

  • Resibufogenin

    Resibufogenin is a cytotoxic steroid isolated from the Chinese drug ChanSu. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological effects on central nervous system.

  • Milrinone

    Milrinone(Win 47203) is a PDE3 inhibitor that increases intracellular cyclic adenosine monophosphate resulting in improved ventricular function and vasodilation.