Tadalafil

CAS No. 171596-29-5

Tadalafil ( IC351, IC-351, IC 351, Tadalafil, Adcirca, Cialis )

Catalog No. M12614 CAS No. 171596-29-5

Tadalafil is a potent phosphodiesterase-5 (PDE5) inhibitor (IC50=1 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG 45 In Stock
50MG 66 In Stock
100MG 101 In Stock
200MG 169 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    Tadalafil
  • Note
    Research use only, not for human use.
  • Brief Description
    Tadalafil is a potent phosphodiesterase-5 (PDE5) inhibitor (IC50=1 nM).
  • Description
    Tadalafil is a potent phosphodiesterase-5 (PDE5) inhibitor (IC50=1 nM); no inhibition on most of the other families of PDEs, with the exception of PDE11.Sexual Dysfunction Approved
  • Synonyms
    IC351, IC-351, IC 351, Tadalafil, Adcirca, Cialis
  • Pathway
    Angiogenesis
  • Target
    PDE
  • Recptor
    PDE5
  • Research Area
    Endocrinology
  • Indication
    Sexual Dysfunction

Chemical Information

  • CAS Number
    171596-29-5
  • Formula Weight
    389.40
  • Molecular Formula
    C22H19N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 52 mg/mL
  • SMILES
    O=C([C@@]1([H])CC2=C([C@@H](C3=CC(OCO4)=C4C=C3)N15)NC6=C2C=CC=C6)N(C)CC5=O
  • Chemical Name
    Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Blount MA, et al. Mol Pharmacol, 2004, 66(1), 144-152.
2. Ring BJ, et al. Clin Pharmacol Ther, 2005, 77(1), 63-75.
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