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Chlorphenesin

CAS No. 104-29-0

Chlorphenesin( Chlorphenesin | NSC 6401 | NSC6401 | NSC-6401 )

Catalog No. M17775 CAS No. 104-29-0

Chlorphenesin is an antigen-associated immunosuppressant that inhibits IgE-mediated histamine release.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Chlorphenesin
  • Note
    Research use only, not for human use.
  • Brief Description
    Chlorphenesin is an antigen-associated immunosuppressant that inhibits IgE-mediated histamine release.
  • Description
    Chlorphenesin is an antigen-associated immunosuppressant that inhibits IgE-mediated histamine release. It is also used as an antimycotic agent.(In Vitro):Chlorphenesin (0.01, 0.1, 0.3%; 30-min exposure) significantly reduces the activity of the Akt pathway in a dose-dependent manner in human meibomian gland epithelial cells (HMGECs).Chlorphenesin (0.1, 0.3%; 24 hours) induces immortalized HMGECs (IHMGECs) rounding, atrophy, poor adherence, detachme and significantly reduces the number of IHMGECs.
  • In Vitro
    Chlorphenesin (0.01, 0.1, 0.3%; 30-min exposure) significantly reduces the activity of the Akt pathway in a dose-dependent manner in human meibomian gland epithelial cells (HMGECs).Chlorphenesin (0.1, 0.3%; 24 hours) induces immortalized HMGECs (IHMGECs) rounding, atrophy, poor adherence, detachme and significantly reduces the number of IHMGECs.
  • In Vivo
    ——
  • Synonyms
    Chlorphenesin | NSC 6401 | NSC6401 | NSC-6401
  • Pathway
    Apoptosis
  • Target
    NF-κB
  • Recptor
    Histamine relase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    104-29-0
  • Formula Weight
    202.63
  • Molecular Formula
    C9H11ClO3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (493.51 mM)
  • SMILES
    OCC(O)COc1ccc(Cl)cc1
  • Chemical Name
    1,2-Propanediol, 3-(4-chlorophenoxy)- (9CI)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Collman J P, et al. ChemInform Abstract: A SILICA-SUPPORTED RHODIUM HYDROFORMYLATION CATALYST: EVIDENCE FOR DINUCLEAR ELIMINATION[J]. 1983, 105(12):7288-7294.
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