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Cerulenin
CAS No. 17397-89-6
Cerulenin ( Cerulenin; Helicocerin; Cephalosporium caerulens; AC1NQZF4; EINECS 241-424-8 )
Catalog No. M12641 CAS No. 17397-89-6
An antifungal antibiotic that inhibits fatty acid synthase (FASN), also blocks cellular proliferation of KRAS-associated lung cancer cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 178 | Get Quote |
|
| 10MG | 265 | Get Quote |
|
| 25MG | 447 | Get Quote |
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| 50MG | 677 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameCerulenin
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NoteResearch use only, not for human use.
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Brief DescriptionAn antifungal antibiotic that inhibits fatty acid synthase (FASN), also blocks cellular proliferation of KRAS-associated lung cancer cells.
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DescriptionAn antifungal antibiotic that inhibits fatty acid synthase (FASN), also blocks cellular proliferation of KRAS-associated lung cancer cells; induces pro-survival, Akt and ERK activation, in serum-deprived KRAS mutant cancer cells; causes a dose-dependent decrease in HER2/neu protein levels in breast cancer cells.
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SynonymsCerulenin; Helicocerin; Cephalosporium caerulens; AC1NQZF4; EINECS 241-424-8
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PathwayMicrobiology/Virology
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TargetFungal
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RecptorFungal
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Research Area——
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Indication——
Chemical Information
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CAS Number17397-89-6
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Formula Weight223.27
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Molecular FormulaC12H17NO3
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Purity>98% (HPLC)
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SolubilityDMSO : 100 mg/mL 447.89 mM
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SMILESCC=CCC=CCCC(=O)C1C(O1)C(=O)N
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Chemical Name(2R,3S)-3-((4E,7E)-nona-4,7-dienoyl)oxirane-2-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Gouw AM, et al. Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):4300-4305.
2. Yellen P, et al. Cancer Lett. 2014 Oct 28;353(2):258-63.
3. Menendez JA, et al. Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10715-20.
2. Yellen P, et al. Cancer Lett. 2014 Oct 28;353(2):258-63.
3. Menendez JA, et al. Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10715-20.
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