Cefoxitin

CAS No. 35607-66-0

Cefoxitin( —— )

Catalog No. M33680 CAS No. 35607-66-0

Cefoxitin (Rephoxitin) is a broad-spectrum, orally available second-generation cephalosporins antibiotic. Cefoxitin interferes with the synthesis of bacterial cell walls.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
500MG 86 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Cefoxitin
  • Note
    Research use only, not for human use.
  • Brief Description
    Cefoxitin (Rephoxitin) is a broad-spectrum, orally available second-generation cephalosporins antibiotic. Cefoxitin interferes with the synthesis of bacterial cell walls.
  • Description
    Cefoxitin, a β-lactam antibiotic, is a broad-spectrum, second-generation cephalosporin. Cefoxitin has a broad spectrum antibacterial activity which includes anaerobic as well as Gram-positive and Gram-negative aerobic bacteria.
  • In Vitro
    Cefoxitin has good activity against Gram-positive bacteria. The MICs for several Gram-positive pathogens are in the range of 1-6 μg/mL.Cefoxitin exhibits high efficacy killing B. burgdorferi at concentration of 1.25 μM/mL.
  • In Vivo
    Cefoxitin (20 mg/kg; i.p.; daily; for 5 days) effectively kills B. burgdorferi in C3H/HeN mice model.Animal Model:Four-week-old female C3H/HeN mice Dosage:20 mg/kg Administration:Intraperitoneal injection, daily, for five consecutive days Result:Had shown high efficacy killing B. burgdorferi in vivo.
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    Cell wall
  • Recptor
    Cell wall | Antibiotic | Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    35607-66-0
  • Formula Weight
    427.45
  • Molecular Formula
    C16H17N3O7S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (233.95 mM; Ultrasonic )
  • SMILES
    [H][C@]12SCC(COC(N)=O)=C(N1C(=O)[C@]2(NC(=O)Cc1cccs1)OC)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. E O Stapley, et al. Cefoxitin and cephamycins: microbiological studies. Rev Infect Dis. Jan-Feb 1979;1(1):73-89.?
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  • Cefoxitin

    Cefoxitin (Rephoxitin) is a broad-spectrum, orally available second-generation cephalosporins antibiotic. Cefoxitin interferes with the synthesis of bacterial cell walls.