
Cefoxitin
CAS No. 35607-66-0
Cefoxitin( —— )
Catalog No. M33680 CAS No. 35607-66-0
Cefoxitin (Rephoxitin) is a broad-spectrum, orally available second-generation cephalosporins antibiotic. Cefoxitin interferes with the synthesis of bacterial cell walls.
Purity : >98% (HPLC)






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Biological Information
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Product NameCefoxitin
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NoteResearch use only, not for human use.
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Brief DescriptionCefoxitin (Rephoxitin) is a broad-spectrum, orally available second-generation cephalosporins antibiotic. Cefoxitin interferes with the synthesis of bacterial cell walls.
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DescriptionCefoxitin, a β-lactam antibiotic, is a broad-spectrum, second-generation cephalosporin. Cefoxitin has a broad spectrum antibacterial activity which includes anaerobic as well as Gram-positive and Gram-negative aerobic bacteria.
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In VitroCefoxitin has good activity against Gram-positive bacteria. The MICs for several Gram-positive pathogens are in the range of 1-6 μg/mL.Cefoxitin exhibits high efficacy killing B. burgdorferi at concentration of 1.25 μM/mL.
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In VivoCefoxitin (20 mg/kg; i.p.; daily; for 5 days) effectively kills B. burgdorferi in C3H/HeN mice model.Animal Model:Four-week-old female C3H/HeN mice Dosage:20 mg/kg Administration:Intraperitoneal injection, daily, for five consecutive days Result:Had shown high efficacy killing B. burgdorferi in vivo.
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Synonyms——
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PathwayImmunology/Inflammation
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TargetCell wall
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RecptorCell wall | Antibiotic | Antibacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number35607-66-0
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Formula Weight427.45
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Molecular FormulaC16H17N3O7S2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (233.95 mM; Ultrasonic )
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SMILES[H][C@]12SCC(COC(N)=O)=C(N1C(=O)[C@]2(NC(=O)Cc1cccs1)OC)C(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. E O Stapley, et al. Cefoxitin and cephamycins: microbiological studies. Rev Infect Dis. Jan-Feb 1979;1(1):73-89.?
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Cefoxitin
Cefoxitin (Rephoxitin) is a broad-spectrum, orally available second-generation cephalosporins antibiotic. Cefoxitin interferes with the synthesis of bacterial cell walls.