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Carbamazepine

CAS No. 298-46-4

Carbamazepine( Carbamazepine, Tegretol, Epitol )

Catalog No. M13912 CAS No. 298-46-4

Carbamazepine, a?sodium channel?blocker, is an anticonvulsant drug.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Carbamazepine
  • Note
    Research use only, not for human use.
  • Brief Description
    Carbamazepine, a?sodium channel?blocker, is an anticonvulsant drug.
  • Description
    Carbamazepine, a?sodium channel?blocker, is an anticonvulsant drug.
  • In Vitro
    Western Blot Analysis Cell Line:3T3-L1 pre-adipocytes Concentration:0-500 μM Incubation Time:10 days Result:Decreased PPAR-γ and C/EPB-α protein levels.Increased ERK 1/2 phosphorylation after a 10?min exposure, and also increased p38 MAPK phosphorylation.
  • In Vivo
    Animal Model:70% Partial hepatectomy treated mice Dosage:250 mg/kg Administration:p.o.Result:Recoverd liver to body weight ratio.Increased the number of BrdU-positive nuclei, Increased PCNA protein.Increased mRNA levels of ccne2 and ccna2.
  • Synonyms
    Carbamazepine, Tegretol, Epitol
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Sodium Channel
  • Recptor
    Sodium Channel
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    298-46-4
  • Formula Weight
    236.27
  • Molecular Formula
    C15H12N2O
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 18 mg/mL (76.18 mM); DMSO: 47 mg/mL (198.92 mM)
  • SMILES
    O=C(C1=CC2=CC=CC=C2NC3=CC=CC=C13)N
  • Chemical Name
    benzo[b][1]benzazepine-11-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Willow M, et al. Mol Pharmacol, 1982, 22(3), 627-635.
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