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Caracemide
CAS No. 81424-67-1
Caracemide( NSC-253272 )
Catalog No. M26639 CAS No. 81424-67-1
Caracemide inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 115 | Get Quote |
|
| 10MG | 165 | Get Quote |
|
| 25MG | 266 | Get Quote |
|
| 50MG | 404 | Get Quote |
|
| 100MG | 593 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameCaracemide
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NoteResearch use only, not for human use.
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Brief DescriptionCaracemide inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.
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DescriptionCaracemide inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.(In Vitro):Caracemide produces severe central nervous system (CNS) toxicity because of the toxic metabolite, methylisocyanate (MIC). Caracemide inactivates R1 by covalent modification at the substrate-binding site.(In Vivo):After administration of Caracemide (6.6 mg/kg;i.p.), the mercapturic acid derivative AMCC was identified in rats urine.
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In VitroCaracemide inactivates R1 by covalent modification at the substrate-binding site and has a toxic metabolite, methylisocyanate (MIC), in vivo.
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In VivoThe mercapturic acid derivative AMCC was identified in urine rats following administration to rats of a single i.p. dose (6.6 mg/kg) of caracemide (NSC-253272). .
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SynonymsNSC-253272
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PathwayOthers
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TargetOther Targets
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RecptorAnti-infection| Bacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number81424-67-1
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Formula Weight189.171
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Molecular FormulaC6H11N3O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (528.63 mM)
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SMILESCNC(=O)ON(C(C)=O)C(=O)NC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Basanti LalHiran, et al. Oxidation of 3,4,5-trimethoxybenzaldehyde by pyridinium fluorochromate in N,N-dimethyl formamide medium: A kinetic and mechanistic study. Arabian Journal of Chemistry. Volume 9, Supplement 1, September 2016, Pages S440-S445
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