Capecitabine ( Ro 09-1978 )

Catalog No. M12189 CAS No. 154361-50-9

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Product Name

Capecitabine
Note

Research use only, not for human use.
Brief Description

Prodrug of 5-Fluorouracil (5-FU). Selectively activated in tumor cells by thymidine phosphorylase; inhibits DNA synthesis upon conversion to 5-FU. Orally available.
Description

Prodrug of 5-Fluorouracil (5-FU). Selectively activated in tumor cells by thymidine phosphorylase; inhibits DNA synthesis upon conversion to 5-FU. Orally available.
Synonyms

Ro 09-1978
Pathway

Cell Cycle/DNA Damage
Target

DNA/RNA Synthesis
Recptor

Thymidine phosphorylase
Research Area

Cancer
Indication

——

CAS Number

154361-50-9
Formula Weight

359.35
Molecular Formula

C15H22FN3O6
Purity

>98%(HPLC)
Solubility

Ethanol: 72 mg/mL (200.36 mM); Water: 6 mg/mL (16.69 mM); DMSO: 72 mg/mL (200.36 mM)
SMILES

O=C(OCCCCC)NC(C(F)=CN1[C@@H]2O[C@H](C)[C@@H](O)[C@H]2O)=NC1=O
Chemical Name

pentyl (1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl)carbamate

1.Lv H, et al. Chin J Y Res. 2014 Dec; 26(6):692-7.

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