Rifapentine ( Cyclopentylrifampicin; DL-473; MDL 473 )

Catalog No. M15311 CAS No. 61379-65-5

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Product Name

Rifapentine
Note

Research use only, not for human use.
Brief Description

Rifapentine is an antibiotic drug used in the treatment of tuberculosis.
Description

Rifapentine is an antibiotic drug used in the treatment of tuberculosis. It inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme.
Synonyms

Cyclopentylrifampicin; DL-473; MDL 473
Pathway

Cell Cycle/DNA Damage
Target

DNA/RNA Synthesis
Recptor

RNA polymerase
Research Area

Infection
Indication

——

CAS Number

61379-65-5
Formula Weight

877.03
Molecular Formula

C47H64N4O12
Purity

>98%(HPLC)
Solubility

Ethanol: 17 mg/mL (19.38 mM); DMSO: 100 mg/mL (114.02 mM)
SMILES

CO[C@H]1/C=C/O[C@]2(Oc(c(C)c3O)c(C2=O)c4c3c(O)c(NC(/C(C)=C\C=C\[C@@H]([C@@H]([C@H]([C@H]([C@H]([C@@H]([C@@H]1C)OC(C)=O)C)O)C)O)C)=O)c(/C=N/N5CCN(C6CCCC6)CC5)c4O)C
Chemical Name

3-(N-(4-Cyclopentyl-1-piperazinyl)formimidoyl)rifamycin

1.Williams DL, et al. Antimicrob Agents ChemOthers. 1998 Jul;42(7):1853-7.

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