Calycosin
CAS No. 20575-57-9
Calycosin( Calycosin )
Catalog No. M13198 CAS No. 20575-57-9
Calycosin (Cyclosin) is a natural active compound with anti-oxidative and anti-inflammation activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 31 | In Stock |
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5MG | 49 | In Stock |
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10MG | 87 | In Stock |
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25MG | 170 | In Stock |
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50MG | 312 | In Stock |
|
100MG | 464 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
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Biological Information
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Product NameCalycosin
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NoteResearch use only, not for human use.
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Brief DescriptionCalycosin (Cyclosin) is a natural active compound with anti-oxidative and anti-inflammation activity.
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DescriptionCalycosin (Cyclosin) is a natural active compound with anti-oxidative and anti-inflammation activity.
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In VitroCell Proliferation Assay Cell Line:MCF-7 cells Concentration:2-32 μM Incubation Time:48 h Result:Increased the MCF-7 cell number at the doses of 2-8 μM.Inhibited the proliferation of MCF-7 cells at the doses of 32 μM.
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In VivoAnimal Model:Adult Male Sprague-Dawley RatsDosage:7.5-30 mg/kg Administration:i.g. daily, 3 days Result:Improved neurological deficit and infarct volum.Reduced the content of malondialdehyde (MDA), protein carbonyl and reactive oxygen species (ROS).Increased the activities of superoxide dismutase (SOD), catalase and glutathione peroxidase (GSH-Px) in a dose-dependent manner.Inhibited the expression of 4-Hydroxy-2-nonenal (4-HNE).
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SynonymsCalycosin
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PathwayOthers
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TargetOther Targets
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RecptorTyrosiN/Ase
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number20575-57-9
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Formula Weight284.26
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Molecular FormulaC16H12O5
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Purity>98% (HPLC)
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SolubilityChloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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SMILESO=C1C(C2=CC=C(OC)C(O)=C2)=COC3=C1C=CC(O)=C3
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Chemical Name7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)chromen-4-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zhou Y, et al. Calycosin induces apoptosis in human ovarian cancer SKOV3 cells by activating caspases and Bcl-2 family proteins. Tumour Biol. 2015 Feb 12.
2. Chen J, et al. Calycosin and genistein induce apoptosis by inactivation of HOTAIR/p-Akt signaling pathway in human breast cancer MCF-7 cells. Cell Physiol Biochem. 2015;35(2):722-8.
molnova catalog
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