Cart
sales@molnova.com
TAS-102
CAS No. 733030-01-8
TAS-102( TAS102, TAS-102, TAS 102, Trifluridine/tipiracil hydrochloride )
Catalog No. M15805 CAS No. 733030-01-8
TAS-102 is an investigational drug candidate for metastatic colorectal Y. It contains trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a molar ratio of 2:1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 30 | In Stock |
|
| 5MG | 47 | In Stock |
|
| 10MG | 80 | In Stock |
|
| 25MG | 143 | In Stock |
|
| 50MG | 237 | In Stock |
|
| 100MG | 357 | In Stock |
|
| 200MG | 538 | In Stock |
|
| 500MG | 842 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameTAS-102
-
NoteResearch use only, not for human use.
-
Brief DescriptionTAS-102 is an investigational drug candidate for metastatic colorectal Y. It contains trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a molar ratio of 2:1.
-
DescriptionTAS-102 is an investigational drug candidate for metastatic colorectal Y. It contains trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a molar ratio of 2:1.
-
In Vitro——
-
In VivoAnimal Model:Male nude mice bearing KM12C, KM12C/5-FU, DLD-1, DLD-1/5-FU, and SC-2 cells Dosage:150 mg/kg/day Administration:p.o.; twice a day for 14 daysResult:Prevented body weight loss and reduced the relative tumor volume in colorectal cancer and gastric cancer mice models.
-
SynonymsTAS102, TAS-102, TAS 102, Trifluridine/tipiracil hydrochloride
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number733030-01-8
-
Formula Weight575.32
-
Molecular FormulaC19H23Cl2F3N6O7
-
Purity>98% (HPLC)
-
SolubilitySoluble in DMSO
-
SMILESO=C1NC(C(C(F)(F)F)=CN1[C@@H]2O[C@H](CO)[C@@H](O)C2)=O.O=C3NC(C(Cl)=C(CN4C(CCC4)=N)N3)=O.[H]Cl
-
Chemical Name4-hydroxy-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(trifluoromethyl)pyrimidin-2(1H)-one compound with 5-chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4-diol (1:1) hydrochloride
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
Egg yolk phosphatidy...
Lecithins, egg can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs.
-
Methoxatin disodium ...
Methoxatin disodium salt an aromatic tricyclic o-quinone is a redox cofactor for bacterial dehydrogenases. It is an efficient electron transfer catalyst from a number of organic substrates to molecular oxygen (O2) constructing quinoprotein model reactions.
-
Albaspidin AA
Albaspidin AA displays strong antibacterial activity against the vegetative form of P. larvae (MIC ranging from 0.168-220 uM).
